Dr D Rico Rodriguez, Dr C Lamb
No more applications being accepted
Funded PhD Project (Students Worldwide)
About the Project
Number of awards
1
Start date and duration
28 September 2020. 3-year PhD
Overview
The genome is identical in every cell of our organism but its three-dimensional (3D) structure is different in every cell type. Genes, enhancers and other regions interact with each other forming 3D genome networks. We analyse the properties of these networks, their sub-communities or fluxes of information, as we do with social networks.
Recent data suggest that genetic variants associated with inflammatory bowel disease (IBD) may be associated with aberrant responses to commensal or pathogenic microbes. However, many of them are in non-coding regions and remain unexplored.
You will investigate the role of microbes as “hidden influencers” of variation in these sequences.
We offer interdisciplinary training opportunities at the interface of bioinformatics, microbiology and immunology, with two main objectives:
-to identify communities of genes and enhancers activated in immune cells in response to microbes
-to uncover associations between IBD variants and enhancers regulating these responses
Sponsor
Newcastle University
Name of supervisors
Daniel Rico https://bit.ly/3asNFgU
Chris Lamb https://bit.ly/2wOtkEb
Robert Hirt https://bit.ly/2UqdZm1
Sophie Hambleton https://bit.ly/2ULob7D
Eligibility Criteria
You must have, or expect to achieve, at least a 2:1 Honours degree in Genetics, Bioinformatics, Immunology or a related area. A further qualification such as an MSc or MRes is advantageous.
As a multidisciplinary project, we don’t expect experience in all areas and any necessary complementary training will be provided during the PhD.
This award is available to UK/EU and international applicants.
To study this course you need to meet the following English Language requirements:
IELTS 6.5 overall (with a minimum of 5.5 in all other sub-skills).
How to apply
You must apply through the University’s online postgraduate application system https://bit.ly/2QUA0Y3
Only mandatory fields need to be completed. However, you will need to include the following information:
-insert the programme code 8300F* in the programme of study section
-select ‘PhD in the Faculty of Medical Sciences – Biosciences’ as the programme of study
-insert the studentship code bi022 in the studentship/partnership reference field
-attach a covering letter and CV. The covering letter must state the title of the studentship, quote the studentship reference code bi022 -and state how your interests and experience relate to the project
-attach degree transcripts and certificates and, if English is not your first language, a copy of your English language qualifications
* The online application system will only allow one application using the programme code 8300F. If you are applying for TWO or more projects using that code then you will need to email our Postgraduate Admissions Service ([Email Address Removed]) with the following information:
-your application number (from the first project application that you submitted online)
-the second studentship code and its corresponding title
-a two page covering letter for the second project
Our Postgraduate Admissions Service will then forward this information to the relevant selector in the Faculty of Medical Sciences.
Contact
Daniel Rico
E-mail: [Email Address Removed]
Tel: +44(0)191 2086931
Funding Notes
100% of UK/EU tuition fees paid and annual living expenses of £15,285 (full award). Successful international candidates will be required to make up the difference between the UK/EU fees and international fees.
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