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PhD in catalysis and natural product synthesis


   School of Physical and Chemical Sciences

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  Dr Stellios Arseniyadis  No more applications being accepted  Funded PhD Project (UK Students Only)

About the Project

The Arseniyadis group (https://arseniyadislab.sbcs.qmul.ac.uk/) is principally interested in the discovery and development of new synthetic methods which allow atom, step and redox-economy while providing high structural and functional complexity as well as stereocontrol. These methods span within the various areas of catalysis which include organic, organometallic and more recently, bio-inspired catalysis. At the core of our research is the will to provide innovative, efficient but also multivalent tools for natural product synthesis and drug discovery. 

The group is looking for two PhD students to work on various projects in collaboration with our industrial partner. This fully-funded PhD studentship is available to develop a range of novel enantioselective metal-catalysed allylic alkylation reactions involving new, bench-stable chiral catalysts, and apply the methods to the synthesis of various biologically relevant targets. This project will be run in collaboration with Servier (France) and can include a secondment at their site. 

The successful applicant will join a highly motivated, productive and friendly research team.

Applicants must have, or expect to obtain, a strong MChem (or equivalent) degree as a requirement of the funding.

Please submit your application by e-mail to Dr Arseniyadis ([Email Address Removed]) including a cv, a cover letter giving your experience and motivation for PhD studies, and contact details for two referees.

Supervisor Contact Details:

For informal enquiries about this position, please contact Stellios Arseniyadis

Tel: 020 7882 8445

E-mail: [Email Address Removed]

Application Method:

To apply for this studentship and for entry on to the Chemistry programme (Full Time) please follow the instructions detailed on the following webpage:

Further Guidance: http://www.qmul.ac.uk/postgraduate/research/

Please note that this studentship is only available to Home applicants. (See: http://www.welfare.qmul.ac.uk/money/feestatus/ for details)

Deadline for applications: May 27 2022


Funding Notes

• Applicant required to start in September 2022.
• The studentship arrangement will cover home tuition fees and provide an annual stipend for up to three years (Currently set for 2021/22 as £17,609).
• The minimum requirement for this studentship opportunity is a good Honours degree (minimum 2(i) honours or equivalent) or MSc/MRes in a relevant discipline.
• If English is not your first language you will require a valid English certificate equivalent to IELTS 6.5+ overall with a minimum score of 6.0 in Writing and 5.5 in all sections (Reading, Listening, Speaking).

References

Selected papers from the group in the field of Pd-AAA:
[1] F. Richard, S. Aubert, T. Katsina, L. Reinalda, D. Palomas, R. Crespo Otero, J. Huang, D. C. Leitch, C. Mateos, S. Arseniyadis* Nature Synthesis 2022 (in press).
[2] T. Katsina, S. Sharma, R. Buccafusca, D. J. Quinn, T. S. Moody, S. Arseniyadis* Org. Lett. 2019, 21, 9348-9352.
[3] S. Aubert, T. Katsina, S. Arseniyadis* Org. Lett. 2019, 21, 2231-2235.
[4] T. Song, S. Arseniyadis,* J. Cossy* Org. Lett. 2019, 21, 603-607.
[5] T. Song, S. Arseniyadis,* J. Cossy* Chem. Eur. J. 2018, 24, 8076-8080 (selected as a Hot Paper).
[6] M. Nascimento de Oliveira, S. Arseniyadis,* J. Cossy* Chem. Eur. J. 2018, 24, 4810-4814.
[7] M. Dolé Kerim, M. Cattoen, N. Fincias, A. Dos Santos, S. Arseniyadis,* L. El Kaïm* Adv. Synth. & Catal. 2018, 360, 449-454.
[8] M. Nascimento de Oliveira, J. Fournier, S. Arseniyadis,* J. Cossy* Org. Lett. 2017, 19, 14-17.
[9] J. Fournier, O. Lozano, C. Menozzi, S. Arseniyadis,* J. Cossy* Angew. Chem. Int. Ed. 2013, 52, 1257-1261.
[10] J. Fournier, S. Arseniyadis,* J. Cossy* Angew. Chem. Int. Ed. 2012, 51, 7562-7566.
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