Improving the resolution in the imaging of biological tissues is of paramount importance for early detection of diseases, as well as their correct diagnosis and cure. The complexity of biological systems makes the imaging particularly difficult and new approaches are needed in order to overcome the current limits.
We aim at using quantum light illumination and demonstrate that this approach provides a quantum advantage in terms of higher sensitivity to the subtle changes to brain tissue at early stages of disease onset.
The biological samples will be placed on nanostructured surfaces, engineered to improve the light-matter interaction, due to the presence of confined optical modes.
Different nanophotonic designs, will be used to this end: photonic crystals, plasmonic structures, gratings.
The student will work on the design, nanofabrication and optical characterisation of nanophotonic devices that will be used as illumination sources. The main techniques involved will include: finite-difference time-domain simulations of electromagnetic wave propagation, nanofabrication (electron-beam lithography, dry and wet etching, scanning electron microscopy, atomic force microscopy), time-resolved photo-luminescence spectroscopy, down to cryogenic temperatures.
Once the source optimised, the student will use quantum light to image brain tissues and explore the new potentiality of quantum light imaging of biological samples for the diagnosis of diseases.
This project will be run as a collaboration between the Integrated Quantum Photonics group, led by Dr Luca Sapienza, and the Extreme Light group, led by Prof. Daniele Faccio.
For more information, please visit our websites: https://sites.google.com/view/integrated-quantum
And contact Dr Luca Sapienza at [Email Address Removed]
How to Apply: Please refer to the following website for details on how to apply: