This collaborative project between the industrial partner Terumo-Aortic and the Glasgow Computational Engineering Centre https://www.gla.ac.uk/research/az/gcec/ will develop and validate computational models for aortic vessels.
Abdominal aortic aneurysms (AAA) are the 13th leading cause of death worldwide. They are usually asymptomatic and upon aneurysm rupture the survival rate is extremely low. Stented endovascular repair is however possible if the aneurysm is detected prior to rupture.
Computational modelling can assist biomedical engineers to optimise stent design and materials selection provided they are rigorously validated. The material properties of the aortic vessel are complex. In addition, the stent is subject to pulsatile loading that can induce fatigue. Then objective of this work is to develop and validate finite element simulations of vessels using experimental data. Such a model is important to Terumo-Aortic for fatigue life assessment of their stent graft design and development.
The choice of model will be informed by the experimental data and the ability to identify the constitutive parameters. The model will account for the inherent uncertainty and sparsity in biological data using a Bayesian approach.
The ideal candidate will have a background in Engineering / Applied Mathematics and familiarity with computational modelling (e.g. the finite element method). The project is part of a larger multidisciplinary and multi-university effort led by Terumo-Aortic. For more information, please contact Andrew McBride [email protected] or Ankush Aggarwal [email protected].
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