The Helmholtz Zentrum München in Munich, Germany, is member of one of the leading research associations in Europe – the Helmholtz Association of German Research Centers. The aim of our research is to proactively detect health risks involving humans and the environment, decoding the mechanisms of pathogenesis and developing concepts for prevention and therapy.
Single-cell technologies have recently gained popularity in biology due to their ability to resolve heterogeneity in cell populations. This has translational impact for example in describing heterogeneities of developmental diseases, cancer or immunology, in particular regarding T-cell heterogeneity during infection processes. Analyzing high-dimensional single-cell data has its own statistical and computational challenges, and standard tools often cannot be applied. The goal of this project is to develop and adapt methods in computational biology to model and analyze transcriptional heterogeneity linked to pathomechanisms and infection.
The project is raised by a collaboration between the Institute of Computational Biology at the Helmholtz Zentrum Munich and the Institute for Medical Microbiology, Immunology and Hygiene at the Technical University of Munich. Job Description Implement, develop and extend methods for processing and analyzing single-cell RNAseq and protein profiles Develop methods for second level analyses, e. g. interaction networks, enrichment analyses Biological interpretation of data Your Qualifications PhD/MSc degree in bioinformatics, computer science, mathematics, physics or equivalent Background in Machine Learning and/or RNAseq analysis Interest in biological applications Passion for science and scientific work Proficient in written and spoken English Being comfortable in interacting with colleagues in an interdisciplinary setting Our Offer Working in an innovative, well-equipped and scientifically stimulating surrounding Further training opportunities Initial short-term employment contract for two–three years with a standard public service salary (TV EntgO Bund EG 13)
The activity involves special knowledge and experience specific to own scientific skills.
The Helmholtz Zentrum München as holder of the Bavarian Advancement of Women Prize and of the Total E-Quality Certificate is striving to increase the overall proportion of women on its staff and thus expressly urges qualified women to apply.
Application documents (motivation letter, CV, certificates, two references) should be submitted as soon as possible as a single PDF file via the online portal: https://fragebogen.candibase.de/helmholtz/mainform.php?param=68a7c2123934fa6382d3c6cdc97c48ae&&lang=en
We are looking forward to receiving your comprehensive online application.
Dr. Anna Sacher Phone: +49(0)89 3187-2926 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Institute of Computational Biology Ingolstädter Landstraße 1 85764 München