Context: The Division of Imaging Mass Spectrometry at M4I is a world-leading institute in high-resolution molecular imaging of biological and material surfaces. The division targets the development and application of state-ofthe-art mass spectrometry-based molecular imaging for biomedical research and food sciences.
Objectives: To assess the differences between traditional and organic wine-making by combining stable isotope analysis with mass spectrometry imaging.
Specific objectives include:
- Determine the molecular composition of commercial fertilisers and biodynamic preparations used in wine production, including identifying different strains of bacteria on the leaves.
- Determine the metabolic composition of organic and industrial wines.
- Understand the effect that biodynamic preparations have on the metabolic composition of vine leaves at high spatial resolution using DESI-IMS, MALDI-IMS and SIMS combined in a multimodal approach; 10 This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement no. 956265.
- Determine specific isotopic ratios (C, N, H, O, Sr and Pb) in wine, leaves and soil to discriminate regional origin using IRMS, MC-ICP-MS and SNIF-NMR.
- Characterise the molecular profile of vine leaves using rapid evaporative ionisation mass spectrometry.
Methodology and Expected Results: Multimodal analysis and data integration for improved wine classification/origin (D1.3); Implementation of fast screening methods for wine traceability (M2); Development of MS methods for determining bioactive compounds in wine (M3).
Planned secondments: S9: JSI (N. Ogrinc), 3 months, M14-16, specific isotopic ratios of light elements in wine, leaves and soil and Sr and Pb isotope analysis; S10: FEM (L. Bontempo), 2 months M19-20 SNIF-NMR analysis and MS database formation; S11: Agilent (J. Escribano), 3 months, M27-29, Target analysis of bioactive compounds by LC-MS.
ESR Profile and requirements:
- Background in Analytical Chemistry, Biochemistry, Food Sciences, Microbiology, Pharmacy or similar.
- Preferably with experience in mass spectrometry, mass spectrometry imaging, separation sciences and bioinformatics.
- Experience with bacterial culture, protein isolation and bacterial identification.
- Outstanding academic study performance.
- You act with attention to quality, integrity, creativity, and cooperation in an international environment. - Critical thinking, flexible, highly motivated and independent
How to apply
Application Process:
All applications, in English, must be done using FoodTraNet application form. To access the application form click on this link:
https://www.foodtranet.org/apply.html
The application form requires basic contact information (name, surname, email) and ESR eligibility criteria (date of Master’s award, full-time postgraduate research experience in months, country of residence and duration of residence in that country). Applicants are invited to choose up to three PhD Positions in order of preference. Only the complete applications (completed application form, CV, Covering Letter and Academic Records) will be evaluated. FoodTraNet is committed to Open, transparent, Merit-based Recruitment procedures of Researchers (OTM-R). Please contact [Email Address Removed] if you have any problems submitting your application.
Please carefully read the Call for Applicants guidance document for more information regarding Employment Conditions, ESR Benefits, and Eligibility Rules before you submit your application: https://www.foodtranet.org/images/call_for_applicants_guidance.pdf .
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