About the Project
With 14,000 alumni present in all economic sectors, the "Institut National des Sciences Appliquées" of Toulouse, an international, pluridisciplinary, state engineering school, is recognised for the excellence of its five-year education which attracts students of a high academic level. The international dimension has been a priority for INSA since it opened and international sections have gradually been set up. On campus, one in five students is an international student.
The position we offer will be embedded at the Toulouse Biotechnology Institute (TBI) within the research group Fermentation Advances and Microbial Engineering (FAME). With its highly developed competences in Life Sciences and Engineering Sciences, TBI implements a scientific strategy that is multi-scale, multidisciplinary and interdisciplinary in order to take up the challenges of bioeconomics with a worldwide collaborative network of public and private contributors (http://www.toulouse-biotechnology-institute.fr/en/presentation_of_lisbp.html). Research activities of the FAME group focus on kinetic and stoichiometric studies ofmicrobial transformations in order to identify the phenomena which limit theperformances of biotechnological processes (http://www.toulouse-biotechnology-institute.fr/en/research/microbial-engineering/fermentation-advances-and-microbial-engineering--ead8.html).
ROLES AND RESPONSIBILITIES
The main part of your PhD research (3 years) will be carried out at INSA Toulouse under the supervision of Prof. Dr. Stéphane Guillouet in the FAME group at the Toulouse Biotechnology Institute. Within these three years an academic research stay (6-7 months) will take place at the Rheinisch-Westfälische Technische Hochschule Aachen (RWTH, Germany) under the supervision of Prof. Dr. Lars Blank. Additionally, an industrial secondment at the company SUEZ Groupe (France) is foreseen. The H2020 Marie Skłodowska-Curie Actions (MSCA) – Innovative Training Network (ITN) project starts in January 2021. The date of recruitment and start of the PhD project is planned for May 2021 and latest on December 2021. Your PhD degree will be awarded based on successful completion of the research work from two universities (INSA, France and RWTH, Germany). You will also be required to participate in the training events and workshops organized by the ITN-European Joint Doctorates (EJD) program. As a Marie Skłodowska-Curie Actions (MSCA) fellow, you are also expected to contribute your time in the dissemination of your PhD project’s result through public engagement and other scientific platforms.
The PhD research will be part of the Work Package 3 “Process intensification of gas-driven processes” of the ConCO2rde project aiming at deciphering the bottlenecks at the technological levels in order to run gas fermentations at high cell densities within pressurized bioreactors in order to speed up the development of the future bioprocess from CO2 as unique Carbon source.
The ESR8 PhD research will focus on the physiology of Cupriavidus necator, under autotrophic conditions and elevated pressure within gas bioreactor for the production of isopropanol:
(i) Interdisciplinary project on system biology, metabolic engineering, fermentation
(ii) Strain engineering for the synthesis of isopropanol,
(iii) Characterization of engineered strains in pressurized bioreactor under autotrophic conditions,
(iv) In-depth analysis of the bacterial metabolism (academic secondment)
(v) Gas transfer performance with industrial gases with the industrial partner.
First supervisor: Prof. Stéphane Guillouet ([Email Address Removed])
Recruiting Institution: INSA Toulouse (France)
Double degree awarding institution: Rheinisch-Westfälische Technische Hochschule Aachen (RWTH, Germany)
• An outstanding M.Sc. degree in Biochemical engineering, Biotechnology, Biochemistry or related field
• Eligible as a graduate student at INSA Toulouse, France
• Research experience in fermentation (bioreactor, microbial kinetics), analytical methods (HPLC, GC, MS, NMR etc.), biochemistry (e.g. protein expression and characterization)
• Ability to work in an international team,
• Inter- and multidisciplinary thinking,
• High motivation,
• An integrative and cooperative personality with excellent communication and social skills,
• Fluency in English – written and oral.
• ESRs must not have resided in the country of the recruiting beneficiary for more than 12 months in the 3 years immediately before the recruitment date (and not have carried out their main activity (work, studies, etc.) in that country) — unless as part of a procedure for obtaining refugee status under the Geneva Convention 1. In addition, local regulations of the host countries may apply. The salary is based on standard living, mobility and family allowances which are adapted to the respective country of recruitment.
• ESRs must be at the date of recruitment an ‘early stage researcher’ (i.e. in the first four years (full-time equivalent research experience) of his or her research career)
• ESRs must not hold a doctoral degree
CONDITION OF EMPLOYMENT
We offer you a work contract in accordance with the Collective Labour Agreement for French Universities.
The salary will range within € 3 783 to € 4 383 pre-tax per month depending on the personal situation
The full time appointment is temporary for a specified period of three years. The preferred starting date is between May 1st and October 1st 2021
To apply for the position, kindly provide:
(i) A letter of motivation including a statement of your research interests, relevant skills and experience;
(ii) A CV including publication list; and
(iii) Names and contact details of three referees willing to write confidential letters of recommendation.
Please upload applications only according to instructions at www.conco2rde.eu.
We are an equal opportunity employer and value diversity at our University. We are committed to building a diverse faculty so you are encouraged to apply. Our selection procedure follows the guidelines of the Recruitment code and European Commission's: European Code of Conduct for recruitment of researchers.
28th of February 2021 11:59pm Central European Time
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 955740.
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