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PhD Position “Interactions of single polymer chains and amyloid fibrils in a thermophoretic trap”


Peter Debye Institute For Soft Matter Physics

Saturday, August 15, 2020 Funded PhD Project (Students Worldwide)

About the Project

A PhD position is available to work under the supervision of Prof. Dr. Frank Cichos at the department Molecular Nanophotonics on the interactions of single polymer chains and the formation of amyloid fibrils in a thermophoretic trap.

We are seeking ahighly motivated PhD candidate with a Master’s degree in Physics with excellent English proficiency. The successful candidatewill perform cutting edge experimental research on the formation of peptide aggregates and the trapping of single and multiple biologically relevant macromolecules in solution. The candidateshould therefore be committed to collaborative and interdisciplinary work, and have excellent oral and written communication skills (records of creative and independent scientific research and active participation in its dissemination in peer-reviewed journals are welcome).

The experimental work will and allow the successful applicant to acquire expert skills and knowledge on optical microscopy, polymer physics, macromolecular dynamics, thermophoresis and protein aggregation. Experience with modern optical microscopy and statistical data analysiswould be useful.

The working language is English. Salaries will be according to DFG standards.

Applications including 1) a letter of interest (max. 1 page), clearly stating the specific motivation of the candidate to join the group, work on this project, career goals, etc., 2) a CV, 3) grade transcripts or equivalent record of excellent academic performance, clearly indicating courses taken andGRADESin each course (for MS and BS), 4) the names of at least two consenting referees should be sent to . The application deadline is August 15,2020.

Reference:
M. Fränzl, T. Thalheim, J. Adler, D. Huster, J. Posseckardt, M. Mertig, F. Cichos
Thermophoretic Trap for Single Amyloid Fibril and Protein Aggregation Studies
Nat. Methods 16, 611–614 (2019)

Please visit our group website for more details about our research:
https://www.uni-leipzig.de/~mona

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