PhD Studentship: Porosity tailored titanium scaffolds for bone engineering
Reference number: CTS2019
Start date of studentship: 1 October 2019
Closing date of advert: 14 May 2019
Interview date: 21 August 2019
Primary supervisor: Dr Carmen Torres-Sánchez
Secondary supervisor: Prof Paul Conway
Replacing a part or a function of the body in a safe, reliable, long-lasting and economic manner is the main motivation of this study. A physiologically acceptable implant requires of its multifunctionality; not only being conducive to regeneration of bone-remodelling cells but it also needs to possess the 3D structure to allow osteoinduction. Titanium and titanium alloys are non-resorbable materials that have proven to be successful as bone replacement or/and bone regeneration matrices. Their non-toxic, bioinert properties as well as their manufacturability to prevent osteopenia derived from a mismatch in mechanical properties make them good contenders in the biomaterials catalogue. Porosity tailoring at a multiscale (i.e. macro, micro and nano) can be exploited to enhance activity at the interface and therefore accelerate the integration into the osteo skeletal system.
Loughborough University is a top-ten rated university in England for research intensity (REF2014). In choosing Loughborough for your research, you’ll work alongside academics who are leaders in their field. You will benefit from comprehensive support and guidance from our Doctoral College, including tailored careers advice, to help you succeed in your research and future career.
Find out more: http://www.lboro.ac.uk/study/postgraduate/supporting-you/research/
The Wolfson School of Mechanical, Electrical and Manufacturing Engineering is renowned for its tradition in manufacturing of multifunctional materials and surfaces that can be used in the bioengineering world
Full Project Detail
This project will explore new manufacturing routes for the porosity tailored metal structures that then will be tested for their chemo-mechanical performance as well as their feasibility as bioengineering scaffolds and medical devices. We are seeking candidates with tissue engineering and biochemistry lab skills and an interest in developing bioengineering cell-based testing skills.
The researcher will join a multidisciplinary team of engineers, physicists and biologists already working on the different aspects of this research topic. The researcher will work in the Multifunctional Materials Manufacturing Lab and the Centre for Biological Engineering at Loughborough University.
Find out more:
Manufacturing at Wolfson: https://www.lboro.ac.uk/departments/meme/research/high-value-manufacturing/
Healthcare engineering: https://www.lboro.ac.uk/departments/meme/research/research-groups/healthcare-engineering/
Applicants should have, or expect to achieve, at least a 2:1 Honours degree (or equivalent) in Bioengineering, Biology, Biochemistry, or any related subjects. Previous experience of work in a tissue engineering or cell-based testing lab will be recommended.
A relevant Master's degree and / or experience in one or more of the following will be an advantage: Biomaterials and Bioengineering, Biochemistry, Pharmacy and Cancer research.
Name: Dr Carmen Torres-Sanchez
Email: [email protected]
Telephone number: +44(0)1509 227518
How to apply
All applications should be made online at http://www.lboro.ac.uk/study/apply/research/
. Under programme name, select ‘PhD in Mechanical Engineering’
Please quote reference number: CTS2019