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  PhD student position - The role of novel molecules and pathways in the pathogenesis of cardiomyopathy and heart failure.


   Department of Internal Medicine

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  Prof NF Frey  No more applications being accepted  Funded PhD Project (Students Worldwide)

About the Project

PhD student position – Molecular Cardiology Lab (m/f/d) wanted for 01.12.2022 at the Department of Internal Medicine III, Clinic for Cardiology, Angiology and Pneumology for the Molecular Cardiology Lab.

 Job-ID: V000010297

Field of application: Clinic for Cardiology, Angiology and Pneumology

Location: Heidelberg

Start date: 01.12.2022

Job Category: Science and teaching

Working hours: Part time (65 %)

Limitation: Temporary (36 months, extension is sought)

Contract: TV-L

Your Tasks

Our Molecular Cardiology lab is inviting applications for a PhD position to investigate the role of novel molecules and pathways in the pathogenesis of cardiomyopathy and heart failure. Our broader translational aim is to explore these molecules as potential targets for therapy which will then be tested in vivo, including utilization of cardiac gene transfer (AAV-based) and small molecule screens. As part of the newly formed CRC 1550 - Molecular Circuits of Heart Disease, we have established collaborations with multiple established PIs within the Heidelberg and Mannheim experimental and clinical cardiovascular communities. As such, successful candidates will have access to state-of-the-art facilities and equipment and the opportunity to thrive in a highly collaborative scientific environment.

In our molecular cardiology lab within a modern research building (“Analysezentrum III”, University Hospital Heidelberg) we offer a dynamic and highly interactive and cross-disciplinary research environment. All OMICs experiments will be analyzed in cooperation with excellent groups on campus (e.g. Prof. Saez-Rodriguez) which offers additional learning opportunities. PhD students will join the Heidelberg Biosciences International Graduate School (HBIGS) and will also take part in a specialized cardiovascular curriculum. As our group is part of the DZHK (“Deutsches Zentrum für Herz-Kreislaufforschung”) you´ll have access to additional education and mentoring programs as well as specific young investigator funding opportunities.

Your Profile

·      Master's degree in a related field such as biology / biochemistry / life sciences

·      Previous experience in molecular biology, biochemistry, -OMICS, and/or genetically modified animal models of cardiac disease will be viewed favorably

·      Basic knowledge on bioinformatics viewed as a plus

·      Ability and desire to work effectively in a team

·      Self-motivated and creative thinker

We offer

·      Goal-oriented, individual training and development opportunities

·      Targeted initial training

·      Job ticket

·      Possibility of childcare (crèche and kindergarten) as well as subsidy for vacation care for school children

·      Active health promotion

·      Company pension plan

·      Access to the university library and other university facilities (e.g. university sports)

Contact & Application

Interested?

Applications will be accepted until 31.10.2022 directly online (https://karriere.klinikum.uni-heidelberg.de/index.php?ac=jobad&id=16948).

Please send a motivation letter outlining your research background and interests, as well as a CV and contact information for previous mentors, as a single PDF to Prof. Dr. med. Norbert Frey ([Email Address Removed]).

Dept. of Internal Medicine III (Cardiology, Angiology and Pneumology)

Prof. Dr. med. Norbert Frey

Heidelberg University Hospital

Im Neuenheimer Feld 410

69120 Heidelberg

[Email Address Removed]

We stand for equal opportunities. Severely disabled persons are given priority in the case of equal suitability. The University Hospital aims to generally increase the proportion of women in all areas and positions in which women are underrepresented. Qualified women are therefore particularly encouraged to apply. Full-time positions are generally divisible, unless there are official or legal reasons to the contrary.

Biological Sciences (4)

References

For more information about our research and methodology please refer to some key publications (e.g. JACC Basic Transl Sci 2021 Mar 17;6(4):365-380. doi: 10.1016/j.jacbts.2021.01.001; Commun Biol. 2020 Oct 9;3(1):562. doi: 10.1038/s42003-020-01289-2; Cardiovasc Res. 2021 Nov 1;117(12):2459-2473. doi: 10.1093/cvr/cvab012; Nat Commun. 2016 Apr 28;7:11317. doi: 10.1315/11317; Circ Res 2012 Dec 7;111(12):1504-16. doi: 10.1161/CIRCRESAHA.112.271007).

 About the Project