PhD studentship in Biosciences - Development of pre-clinical 3D models of liver cancer to test novel therapies
This is a unique opportunity to undertake a collaborative interdisciplinary PhD research project in biomedical science and tissue engineering in internationally leading research laboratories at Newcastle University. You will join a highly motivated and dynamic research team delivering high-quality translational research in liver cancer biology, drug discovery and tissue engineering.
Hepatocellular carcinoma (HCC) is the second common cause of cancer deaths worldwide. It often develops on the background of chronic liver disease, with multiple cellular interactions between the tumour, immune system and hepatic microenvironment all influencing cancer growth. HCC biology and immunotherapies are rapidly evolving, but a barrier to advance basic discoveries is a lack of clinically relevant pre-clinical models to test emerging therapies.
The student will utilise novel 3D bioprinting and tissue slice technology to bioengineer physiologically relevant rodent and human in vitro models of liver cancer to study tumour-liver-immune cell interactions and test immunotherapies. This crosscutting project will facilitate creative thinking and technical innovation.
Newcastle University (http://bitly.ws/87Qx)
Name of supervisor(s):
Professor Fiona Oakley, Professor Derek Mann, Professor Helen Reeves and Professor Kenny Dalgarno.
You must have, or expect to achieve, at least a 2:1 Honours degree in Biochemistry, Microbiology, Biosciences or a related area. A further qualification such as an MSc or MRes is advantageous.
This award is available to UK/EU and international applicants.
To study this course you need to meet the following English Language requirements:
IELTS 6.5 overall (with a minimum of 5.5 in all other sub-skills).
How to apply:
You must apply through the University’s online postgraduate application system. To do this please ‘Create a new account’ (http://bitly.ws/87Qz).
Only mandatory fields need to be completed. However, you will need to include the following information:
• insert the programme code 8300F* in the programme of study section
• select ‘PhD in the Faculty of Medical Sciences – Biosciences’ as the programme of study
• insert the studentship code BI024 in the studentship/partnership reference field
• attach a covering letter and CV. The covering letter must state the title of the studentship, quote the studentship reference code BI024 and state how your interests and experience relate to the project
• attach degree transcripts and certificates and, if English is not your first language, a copy of your English language qualifications.
* The online application system will only allow one application using the programme code 8300F. If you are applying for TWO or more projects using that code then you will need to email our Postgraduate Admissions Service ([Email Address Removed]) with the following information:
your application number (from the first project application that you submitted online)
the second studentship code and its corresponding title
a two page covering letter for the second project
Our Postgraduate Admissions Service will then forward this information to the relevant selector in the Faculty of Medical Sciences.
100% of UK/EU tuition fees paid and annual living expenses of £15,285 (full award). Successful international candidates will be required to make up the difference between the UK/EU fees and international fees.