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PhD Studentship in Cancer Research - Targeting glycan sugar groups to improve the diagnosis and treatment of prostate cancer

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  • Full or part time
    Dr J Munkley
  • Application Deadline
    No more applications being accepted
  • Funded PhD Project (Students Worldwide)
    Funded PhD Project (Students Worldwide)

Project Description

Number of awards
1

Start date and duration
28 September 2020. 3 Year PhD

Overview
This PhD project will explore if glycan sugars can be exploited to improve the diagnosis and treatment of prostate cancer.

We have developed a glycan based blood test (known as GlycoScore) that can be used to differentiate benign and aggressive prostate cancer. This PhD project will further develop/validate our GlycoScore test by testing multiple large independent cohorts.

Our findings also suggest glycans regulate key oncogenic signalling pathways in prostate cancer and that this can be inhibited using existing glycan targeting drugs. The project will also use pre-clinical models and novel multi-omic studies to test if existing glycan targeting drugs can be repurposed as new treatments for prostate cancer.

Sponsor
Newcastle University

Name of supervisor(s)
Dr Jennifer Munkley (https://bit.ly/2ybmPvD), Biosciences Institute (https://bit.ly/2UiVUXi)
Dr Rakesh Heer (https://bit.ly/33JdlDe), Translational and Clinical Research Institute (https://bit.ly/2wCTARF)
Professor David Elliott (https://bit.ly/33JOVcU), Biosciences Institute

Eligibility Criteria
You must have, or expect to achieve, at least a 2:1 Honours degree in Genetics, Biology, Biochemistry, Cancer Research or a related area. A further qualification such as an MSc or MRes is advantageous.

This award is available to UK/EU and international applicants.

To study this course you need to meet the following English Language requirements:

IELTS 6.5 overall (with a minimum of 5.5 in all other sub-skills).

How to apply
You must apply through the University’s online postgraduate application system. To do this please ‘Create a new account’ (https://bit.ly/33MEB44).

Only mandatory fields need to be completed. However, you will need to include the following information:

insert the programme code 8300F* in the programme of study section
select ‘PhD in the Faculty of Medical Sciences – Biosciences as the programme of study
insert the studentship code BI016 in the studentship/partnership reference field
attach a covering letter and CV. The covering letter must state the title of the studentship, quote the studentship reference code BI016 and state how your interests and experience relate to the project
attach degree transcripts and certificates and, if English is not your first language, a copy of your English language qualifications

* The online application system will only allow one application using the programme code 8300F. If you are applying for TWO or more projects using that code then you will need to email our Postgraduate Admissions Service ([Email Address Removed]) with the following information:

your application number (from the first project application that you submitted online)
the second studentship code and its corresponding title
a two page covering letter for the second project

Our Postgraduate Admissions Service (https://bit.ly/2wqmwwp) will then forward this information to the relevant selector in the Faculty of Medical Sciences.

Contact
Dr Jennifer Munkley [Email Address Removed]

Funding Notes

100% of UK/EU tuition fees paid and annual living expenses of £15,285 (full award). Successful international candidates will be required to make up the difference between the UK/EU fees and international fees.



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