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PhD studentship in Immunology - Biomaterial-based therapeutics for in vivo induction of tolerogenic dendritic cells (BioTol).

Translational and Clinical Research Institute

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Dr C Hilkens No more applications being accepted Funded PhD Project (European/UK Students Only)

About the Project

Number of awards:

Start date and duration:
1 October 2020 for 4 years.

This project aims to develop novel immunotherapeutics for the restoration of immune tolerance in patients suffering from rheumatoid arthritis. The objective is to design and test an injectable therapeutic biomaterial (coined BioTol) that will induce the generation of tolerogenic dendritic cells in vivo. You will work in a multidisciplinary team based at the Universities of Newcastle and Glasgow, comprising immunologists with expertise in therapeutic immunomodulation, and a biomaterial engineer specialized in building novel and intelligent biomaterials for in vivo application.

You will spend the first 2 years of the project at Newcastle University, where BioTol engineering and in vitro testing will take place, before moving to the University of Glasgow where BioTol will be tested in an in vivo arthritis model.

You will be part of The Research into Inflammatory Arthritis Centre Versus Arthritis (RACE) is a collaboration between the Universities of Birmingham, Glasgow, Newcastle and Oxford, with funding and support from Versus Arthritis. The programme capitalises on the expertise of the contributing academic institutions, and offers an outstanding opportunity for students to undertake excellent project-based research training within world-class research environments.

The Research into Inflammatory Arthritis Centre Versus Arthritis (RACE) (http://www.race-gbn.org)

Name of supervisor(s):
Dr Catharien Hilkens, Translational and Clinical Research Institute, Newcastle University

Dr Katarina Novakovic, School of Engineering, Newcastle University

Professor James Brewer and Professor Paul Garside, University of Glasgow

Eligibility Criteria
Applicants must have, or expect to achieve, at least a 2:1 honours degree or international equivalent, in a biological or related subject. A Masters (MRes or MSci) qualification may be advantageous.

The award is available to UK/EU applicants only.

How to apply
You must apply through the University’s online postgraduate application system by creating an account (https://www.ncl.ac.uk/postgraduate/apply/). To do this please select ‘How to Apply’ and choose the ‘Apply now’ button.

Select ‘Create new account’.

Only mandatory fields need to be completed. However, you will need to include the following information:

insert the programme code 8300F in the programme of study section
select ‘PhD in the Faculty of Medical Sciences’ as the programme of study
insert the studentship code TC001 in the studentship/partnership reference field
attach a covering letter and CV. The covering letter must state the title of the studentship, quote the studentship reference code TC001 and state how your interests and experience relate to the project
attach degree transcripts and certificates and, if English is not your first language, a copy of your English language qualifications.
Please also send a Cover letter and CV to: [Email Address Removed].

Funding Notes

Support includes an annual stipend at RCUK rate for 4 years (amount for 2019/20 was £15,009), PhD registration fees at UK/EU student rate, research expenses and travel costs.
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