Ion channels in living cells are examples of where quantum effects can play a role in biology. These proteins provide a selective conduction of ions across cellular membranes, which is crucial for cell survival. The quantum mechanisms behind how channels select and transport certain ions, whilst rejecting others, are still poorly understood. This exciting project aims to investigate these experimentally, whilst at the same time simulating the effects of transport of different ions through the epithelial sodium channel. We will iteratively test and refine a simulation of ion selectivity through the channel pore, whilst experimentally measuring the channel kinetics.
This is a three-year project commencing in October 2020.
Entry requirements: Applicants are expected to hold a first or upper-second class degree (or equivalent overseas qualification), or a lower second plus a good Masters degree (distinction normally required) in chemistry, biological or physical sciences, ideally with computer modelling/simulation experience. Cell culture techniques would be an advantage. IELTS requirements: 6.5 or above (or equivalent) with 6 in each individual category.
How to apply: Applications should be made through the PhD Biosciences and Medicine course page: https://www.surrey.ac.uk/postgraduate/biosciences-and-medicine-phd. Please state the studentship title and supervisor on your application. When the system asks you to add your ‘Research Project’ please copy and paste the project description of the project you wish to apply for.