About the Project
Recent evidence suggests that aging processes heavily contribute to ECM remodelling in cardiac tissues. To date, our knowledge on (1) how ageing influences ECM composition, (2) whether and how an aged matrix can affect the regenerative capacity of cardiac cells, (3) the impact of a aged ECM on cell-to-cell communication, (3) the impact on an aged ECM on cardiac therapeutic intervention. The aim of this proposal will be to develop an in vitro model of cardiac tissue ageing, to explore how ageing affects the ability of the ECM components to modulate the conductivity, mechanical properties as well as the intrinsic electrophysiological and molecular properties of cardiac cells.
This is a three year project commencing in October 2020.
• MSc degree or European equivalent degree in a relevant scientific or biomedical discipline (candidates with a medical or veterinary background need not have an MSc)
• Excellent communication and organisational skills
• Ability to work independently and as part of a team
• Experience with basic molecular techniques
How to apply:
Applications should be made through the Biosciences and Medicine PhD course page: https://www.surrey.ac.uk/postgraduate/biosciences-and-medicine-phd#apply
Please clearly state the studentship title and supervisor on your application.
Applicants are advised to contact the primary supervisor Kamalan Jeevaratnam, [Email Address Removed], for informal enquiries before applying for the studentship.
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