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PhD Studentship Opportunity: Modeling immuno-metabolic alterations in diseases using single cell and spatial multi'omic technologies

   School of Biosciences and Medicine

  Prof Paul Townsend  Thursday, November 18, 2021  Funded PhD Project (Students Worldwide)

Guildford United Kingdom Biochemistry Bioinformatics Cancer Biology Cell Biology Immunology Molecular Biology

About the Project

This studentship aims at exploring the metabolic and immunological mechanisms involved in disease pathogenesis of multiple diseases such as Cancer, autoimmunity and viral infections. You will be able to explore multimodal data acquired using various technologies such as single-cell RNAseq, CITE-seq etc; as well as multiple single-cell, spatial and 3D metabolomic data acquired using the latest technologies available such as mass-spectrometry analysis but also deep-immunophenotyping. The candidate will be instrumental in helping the lab to decipher altered metabolic routes altered in specific pathologies for further exploration in the lab.

The candidate will have a strong knowledge in R/Rstudio and will be familiar with the various and latest analysis scripts such as Seurat, monocle etc. You will also benefit from state-of-the-art platforms and facilities available at the University of Surrey and with our industrial partners. The project will also be benefit from collaboration with International partners.

Knowledge of the immune system and other programming language such as Python will be a great advantage; and the student will get intense training on areas of interests/needs.

Supervisors: Prof Paul A. Townsend and Olivier NF. Cexus

This is a 3.5 year project starting in January 2022 or October 2022.

Entry requirements

A First or Upper Second-Class Honours degree from the UK (or equivalent qualification from international Institutions) in a relevant subject area. Candidate with strong programming expertise in R, R Studio; and in the analysis package Seurat, Monocle, etc. are strongly encouraged to apply. Basic knowledge of biological processes / Immune system is a strong plus.

English language requirements: An IELTS Academic of 6.5 or above with 6 in each individual category (or equivalent qualification from other agencies). 

How to apply

Applications should be submitted via the online application portal for Biosciences and Medicine PhDs. Please state clearly the project that you are applying for and your supervisor.

We encourage informal enquiries to be sent to Prof Paul A. Townsend () and/or Dr Olivier NF. Cexus (

Funding Notes

UKRI-aligned stipend (£15,609 pa for 2021-22), approved University of Surrey fees and a research budget.

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