University of Hong Kong Featured PhD Programmes
Imperial College London Featured PhD Programmes
Peter MacCallum Cancer Centre Featured PhD Programmes

Photochemical synthesis of new drug-like scaffolds

School of Chemistry

, Applications accepted all year round Self-Funded PhD Students Only

About the Project

"Our laboratory is interested in the application of enabling technologies, such as continuous flow[1] and photochemistry,[2] for the synthesis of useful functional molecules such as drugs, agrochemicals and materials. Advantageously, these continuous-flow photoreactors are easier to use and control than their batch-wise predecessors. Photochemical reactions behave in an orthogonal manner from thermally-allowed reactions and offer a unique route to unusual scaffolds. The construction of these unusual scaffolds is of interest to commercial drug-discovery programmes as they have not be tested on drug targets and offer new opportunities to target diseases. During this project we will develop novel photochemical strategies towards new biologically-interesting molecules with a view to synthesizing small libraries for further testing.

In addition to the flow-photochemical equipment the Department of Chemistry possess state-of-the-art equipment for the characterization of these compounds through the Chemical Analysis Facility (CAF including: NMR up to 700 MHz; molecular spectroscopy (Raman, UV/Vis, IR and fluorescence); gas- and liquid-chromatography mass spectrometry (GC-MS and LC-MS); single-crystal and powder X-ray analysis; thermal analysis (TGA); and electron microscopy.

This project will involve training in flow chemistry and organic synthesis and as such will allow you to develop excellent practical and theoretical skills in synthetic chemistry. "


"[1] J. S. Moore, C. D. Smith, and K. F. Jensen, React. Chem. Eng., 2016, 1, 272–279.
[2] D. Chappell, M. G. B. Drew, S. Gibson, L. M. Harwood, and A. T. Russell, Synlett, 2010, 517-520."

Email Now

Insert previous message below for editing? 
You haven’t included a message. Providing a specific message means universities will take your enquiry more seriously and helps them provide the information you need.
Why not add a message here

The information you submit to University of Reading will only be used by them or their data partners to deal with your enquiry, according to their privacy notice. For more information on how we use and store your data, please read our privacy statement.

* required field

Your enquiry has been emailed successfully

FindAPhD. Copyright 2005-2020
All rights reserved.