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Phytochrome: from photochemistry to signal

  • Full or part time
  • Application Deadline
    Tuesday, April 23, 2019
  • Funded PhD Project (Students Worldwide)
    Funded PhD Project (Students Worldwide)

Project Description

A PhD position at the Institute for Plant Physiology of the Justus Liebig University is available immediately. The position (E13 65%) is funded for three years as part of the project "Phytochrome from photochemistry to signalling" (DFG Hu702/12) in collaboration with Chen Song in Jörg Matysik’s lab in Leipzig.
The aim of the project is to further our understanding of the functional mechanism underlying photoconversion and signal activation in the cyanobacterial phytochrome Cph1. To this end we will study the structures of the Pr and Pfr parent states as well as those of photocycle intermediates with the help of crystallographic and solid-state NMR methods, work that has already lead to numerous prominent publications. The successful candidate will work closely with Soshi Nagano in the Giessen lab to create appropriate derivatives of Cph1 for crystallisation and highly-accurate atomic distance determinations. The work will include visits to various international research facilities and extensive personal interactions both in the co-operating labs as well as with members of the Sfb1078 collaborative research group in Berlin.

Funding Notes

The candidate should have graduated in biochemistry, molecular biology or a related field. Experience in protein biochemistry and/or physicochemical analysis of protein structure/function would be an advantage. Proficiency in written and spoken English and ability to work constructively in a multinational, interdisciplinary team are important. Applications from women and disabled persons are especially welcome.
Interested candidates should initially apply by e-mail including a tabular CV to (Professor Jon Hughes, Plant Physiology, JLU Giessen, Germany).

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