About the Project
Despite the central importance of gravitropic response for the control of plant form, the mechanisms by which roots and shoots maintain vertical growth are relatively poorly understood. Recent discoveries in the Kepinski group at the University of Leeds have provided a new way to approach this fascinating question. Using new mutants, proteomics, and state-of-the-art imaging techniques, including vertical-stage confocal microscopy, this project will allow you to explore the biophysical and molecular basis of the perception of gravity and the ensuing gravitropic response. The project will also involve collaboration with physicists and mathematical modellers and is thus an exciting opportunity to make important discoveries in plant biology while at the same time receiving a training that is truly interdisciplinary.
Potential applicants are encouraged to contact Dr Stefan Kepinski ([Email Address Removed]) if they would like to discuss the project.
Candidates should have/be expecting a 2.1 or above at undergraduate level in a relevant area. If English is not your first language, you will be required to meet our language entry requirements. The PhD is to start in Oct 2020.
Please apply online https://studentservices.leeds.ac.uk/pls/banprod/bwskalog_uol.P_DispLoginNon and include project title and supervisor name, and upload a CV and transcripts.
Huang, G., Liang, W., Sturrock, C.J., Pandey, B., Giri, J., Mairhofer, S., Wang, D., Muller, L., Tan, H., York, L.M., Yang, J., Song, Y., Kim, Y, Qiao, Y., Xu, J., Kepinski, S., Bennett, M.J., and Zhang, D. (2018) Rice actin binding protein RMD controls crown root angle in response to external phosphate. Nature Communications 9:2346 DOI: 10.1038/s41467-018-04710-x
Roychoudhry, S, Kieffer, M, Del Bianco, M, Liao, C, Weijers, D and Kepinski, S. (2017) The developmental and environmental regulation of gravitropic setpoint angle in Arabidopsis and bean. Scientific Reports 7:42664 DOI: 10.1038/srep42664
Wang, R., Zhang, Y., Kieffer, M., Yu, H., Kepinski, S., and Estelle, M. (2016) HSP90 regulates temperature-dependent seedling growth by stabilizing the auxin receptor F-box protein TIR1. Nature Communications 7:10269. doi: 10.1038/ncomms10269.
Roychoudhry, S. and Kepinski, S. (2015) The analysis of gravitropic setpoint angle control in Arabidopsis. Methods in Molecular Biology 1309:31-41. doi: 10.1007/978-1-4939-2697-8_4.
Roychoudhry, S. and Kepinski, S. (2015) Root and shoot branch growth angle control – The wonderfulness of lateralness. Current Opinion in Plant Biology 23:124-131
Roychoudhry, S., Del Bianco, M., Kieffer, M., Kepinski, S. (2013) Auxin controls gravitropic setpoint angle in higher plant lateral branches. Current Biology 23(15):1497-504. doi: 10.1016/j.cub.2013.06.034.
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