£6,000 PhD Scholarship | APPLY NOW £6,000 PhD Scholarship | APPLY NOW
Gdansk University of Technology Featured PhD Programmes
FindA University Ltd Featured PhD Programmes

Polyphenol exposure and cardiometabolic outcomes among breast cancer survivors – a prospective biomarker study


   School of Biological Sciences

This project is no longer listed on FindAPhD.com and may not be available.

Click here to search FindAPhD.com for PhD studentship opportunities
  Dr Tilman Kuhn  Applications accepted all year round  Self-Funded PhD Students Only

About the Project

Polyphenol intake protects against cardiovascular diseases in the general population, while not much is known about its health effects among cancer survivors. We will use a large prospective study among breast cancer survivors to evaluate associations between polyphenol exposure (biomarkers and intake) in relation to cardiometabolic disease risks.    

Polyphenols have been shown to protect against several cardiometabolic diseases in the general population. Many cancer survivors have increased cardiometabolic risks, in part due to long-term side effects of cancer treatments. However, it is not known whether polyphenols may mitigate cardiometabolic disease risks among people with cancer. At the same time, there is preliminary evidence to suggest that certain polyphenols may inhibit the efficiency of cancer treatments, but larger human studies are lacking. 

We will evaluate associations between polyphenol exposure, assessed by comprehensive questionnaire and biomarker data, and risks of common cardiometabolic outcomes among breast cancer survivors. These outcomes include myocardial infarction, stroke, and diabetes, but also cardiovascular as well as overall mortality. Data from a cohort of 2,000 women, who were followed up for more than 15 years after diagnosis, will be used. Potential interactions between polyphenols and cancer treatments will be analysed in relation to prospective outcomes.  

Search Suggestions
Search suggestions

Based on your current searches we recommend the following search filters.

PhD saved successfully
View saved PhDs