This is a 4 year BBSRC studentship under the Newcastle-Liverpool-Durham DTP. The successful applicant will receive research costs, tuition fees and stipend (£15,009 for 2019-20). The PhD will start in October 2020. Applicants should have, or be expecting to receive, a 2.1 Hons degree (or equivalent) in a relevant subject. EU candidates must have been resident in the UK for 3 years in order to receive full support. Please note, there are 2 stages to the application process.
Identification and Characterization of Canine Ligament Progenitor Cells and Their Extracellular Matrix Niche.” J Proteome Res 18(3): 1328-1339. (2019).
Variations during ageing in the three-dimensional anatomical arrangement of fascicles within the equine superficial digital flexor tendon.” Eur Cell Mater 35: 87-102. (2018)
Cross-species gene modules emerge from a systems biology approach to osteoarthritis.” NPJ Syst Biol Appl 3: 13 (2017).
Matrix metalloproteinase 14 is required for fibrous tissue expansion.” eLife. 4: e09345 (2015).
Stepwise proteolytic activation of type I procollagen to collagen within the secretory pathway of tendon fibroblasts in situ.” Biochem J 441(2): 707-717. (2012).
Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis.” Nature Commun 9:256. (2018)
The aldehyde dehydrogenase AldA contributes to the hypochlorite defense and is redox-controlled by protein S-bacillithiolation in Staphylococcus aureus” Redox Biol 15:557-568 (2018)
A proton relay enhances H2O2 sensitivity of GAPDH to facilitate metabolic adaptation.” Nat Chem Biol 11:156-63 (2015)
Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes. Proc Natl Acad Sci U S A. 111:E3177-86 (2014)
Live Imaging of Cell Invasion Using a Multicellular Spheroid Model and Light-Sheet Microscopy” Adv Exp Med Biol 1035:155-161 (2017)