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Post-Translational Modifications Orchestrate Organ Symmetry (MOUBAYIDINJ20DTP)

  • Full or part time
  • Application Deadline
    Monday, November 25, 2019
  • Competition Funded PhD Project (European/UK Students Only)
    Competition Funded PhD Project (European/UK Students Only)

Project Description

A major challenge during morphogenesis includes the establishment of symmetry types, such as radial and bilateral symmetry: a developmental commitment which greatly impacts on organ function. In humans, defects in organ-symmetry establishment leads to malformation and diseases, but despite its importance, our knowledge about symmetry foundation in multicellular organisms is very limited. Less intuitively, organ symmetry establishment is fundamental for plant survival too.
Therefore, the aim of this project is to shed light on a new mechanism regulating radial and bilateral
symmetry establishment during plant organogenesis, using A.thaliana as a model.You will investigate how a specific post-translational modifications underpins direct protein interactions
between key regulators of plant organ symmetry, which in turn switches on and off gene expression, precisely and quickly, during organ development.

The research programme will provide you with the opportunity to develop the skills and expertise to work at the cutting edge of biological science. Examples include several microscopy techniques (optical, confocal and electron microscopes) as well as proteomics, genetics, and molecular experiments, all of which will greatly enhance your research portfolio. You will be based in the Department of Crop Genetics under Dr Moubayidin’s direct supervision in a highly stimulating environment. Moreover, you will be inducted into the existing JIC post-graduate training and mentoring programme, where you will receive a range of scientific training suited to the programme of work. Also, you will benefit from attending relevant national and international conferences and outreach events to communicate your results and networking within the wider academic community.

This project has been shortlisted for funding by the Norwich Biosciences Doctoral Training Partnership (NRPDTP). Shortlisted applicants will be interviewed as part of the studentship competition. Candidates will be interviewed on either the 7th, 8th or 9th January 2020.

The NRP DTP offers postgraduates the opportunity to undertake a 4-year research project whilst enhancing professional development and research skills through a comprehensive training programme. You will join a vibrant community of world-leading researchers. All NRPDTP students undertake a three-month professional internship (PIPS) during their study. The internship offers exciting and invaluable work experience designed to enhance professional development. Full support and advice will be provided by our Professional Internship team. Students with, or expecting to attain, at least an upper second-class honours degree, or equivalent, are invited to apply.

For further information and to apply, please visit our website: https://biodtp.norwichresearchpark.ac.uk/

Funding Notes

For funding eligibility guidance, please visit our website: View Website. Full Studentships cover a stipend (2019/0 rate: £15,009pa), research costs and tuition fees at UK/EU rate and are available to UK and EU students who meet the UK residency requirements.

Students from EU countries who do not meet the UK residency requirements may be eligible for a fees-only award. Students in receipt of a fees-only award will be eligible for a maintenance stipend awarded by the NRPDTP Bioscience Doctoral Scholarships. To be eligible students must meet the EU residency requirements.

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