About the Project
Heart failure is one of the world’s biggest killers. In this multidisciplinary PhD project, you will work across two labs to bridge the divide between cardiovascular science and chemistry. We have identified a new strategy that could potentially be used to treat heart failure that relies on targeted protein degradation, an emerging strategy in medicinal chemistry. In this project, you will make a new set of small molecules called proteolysis targeting chimeras (PROTACs) and test them for efficacy against phospholamban, a key regulator of cardiac function. Knowledge of both cell biology and synthetic chemistry is essential, with experience in both a further positive.
The MVLS/EPSRC grant provides tuition fees and stipend of at least £15,285 (UKRI rate 2020/21).
Please view application information here: https://www.gla.ac.uk/colleges/mvls/graduateschool/mvlsepsrcstudentships/
Once you have all the required application documentation, please apply here: https://www.gla.ac.uk/study/applyonline/?CAREER=PGR&PLAN_CODES=ZY38-7316
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