Proteomic Markers of Chronic Renal Scarring
All types of chronic kidney disease (CKD) progress to end stage renal failure through a common pathway of fibrosis and scarring. Subsequently 2 million patients worldwide require renal replacement therapy (RRT). A key research objective is the identification of biomarkers that can be used to determine the rate of decline of renal function and thus inform treatment strategies. The aim of this project is to use samples from a large biorepository of kidney disease patients to both study the expression of known markers of renal damage and to use proteomic methods to identify proteins related to the kidney scarring process. This data will be combined with longitudinal measurements of renal function and used to assess access existing markers of disease progress and identify potentially novel molecules with diagnotic and prognostic value.
Open to Home/EU and Overseas students that have secured funding for their studies. Candidates must have a first or upper second class honours degree or equivalent.
Interested candidates should in the first instance contact Dr Phil Watson [Email Address Removed]
How to apply
How to apply:
Please complete a University Postgraduate Research Application form available here: www.shef.ac.uk/postgraduate/research/apply
Please clearly state the prospective main supervisor in the respective box and select 'Oncology & Metabolism' as the department.