The only part of the human brain that can be visualised non-invasively is the retina, situated at the back of the eye. In recent years it has been shown that neuronal dysfunction affecting the rest of the brain can be detected within the retina, sometimes earlier than other neurological symptoms can be detected. This project aims to characterise the function of neurotransmitter systems in the retina, such as dopamine and acetylcholine, and apply that knowledge to diagnose diseases such as Parkinson’s, Alzheimer’s, ADHD and diabetes.
We are offering a research scholarship to a highly motivated PhD candidate to work within a larger research group focusing on “Neuroscience Research into Ageing” funded by the Ainsworth Medical Research Innovation Fund. This project will primarily involve in vivo work with rodents paired with translation to human subjects. Techniques involved in this project will include electroretinogram (ERG), in vitro single-cell electrophysiology, mass spectrometry, immunohistochemistry and molecular biology.