We are currently seeking a highly motivated individual to join our team in investigating the role of RNA metabolism in motor neuron disorders (MNDs). MNDs encompass a group of neurodegenerative diseases that primarily affect motor neurons, which are responsible for controlling skeletal muscle contraction and facilitating movement. By exploring the underlying mechanisms of neurodegeneration, we aim to shed light on the pathogenesis of these disorders.
As a successful candidate, you will employ a combination of cutting-edge techniques, including systems biology, biochemical analysis, and imaging approaches. Examples of the techniques you will utilize include Ribo-seq, CLIP-seq, and CRISPR-mediated gene editing. Moreover, you will have the opportunity to work with compartmentalized neuronal cultures in hiPSC-based differentiation systems, building upon the research by Zappulo et al. (2017), Ludwik et al. (2019), Ciolli et al. (2019), and Mendonsa et al. (2023). Further information about our project can be found at www.chekulaevalab.org.
The ideal candidate for this position should possess a Master's degree in biology, biochemistry, or molecular biology. Experience in molecular biology techniques and cell culture is essential, and a keen interest in RNA biology and mechanisms of gene regulation is highly desirable. Proficiency in spoken and written English is necessary for effective communication within our international team. Previous experience in hiPSC work and RNA biology techniques will be considered a distinct advantage.
To apply, please submit your motivation letter and CV, including the contact details of at least two referees, to marina.chekulaeva(at)mdc-berlin.de. We look forward to receiving your application and potentially welcoming you to our dynamic research group.
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