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Role of cytokines in the immunopathogenesis of hypertension

Project Description

Applications are invited for a three-year full time PhD studentship within the Institute of Cardiovascular and Medical Sciences.

Prof Tomasz Guzik from the University of Glasgow have received a major grant from the European Research Council (ERC Consolidator Grant) for a study to investigate the role of new inflammation-related mechanisms of hypertension. This interdisciplinary project aims to identify novel biomarkers and therapeutic targets for use in improving the diagnosis, understanding and treatment of hypertension. The project is conducted in collaboration between Institute of Cardiovascular and Medical Sciences and Institute of Infection, Immunity and Inflammation. Preliminary studies from this collaboration show possible key regulatory role of cytokines such as IL-33 in this process.

The PhD Fellow will receive maximal exposure to state of the art technology in vascular and cardiac biology field. Training in immunology, vascular biology, models of hypertension, vascular function assessment, vascular oxidative stress and cell culture will be available as part of the project.

Applicants will normally be expected to reside (or have residency) within the UK/EU. Applicants should have obtained, or expect to obtain a 2:1 or 1st Class Honours degree in a relevant subject. Support includes an annual stipend at RCUK rates for 3 years, PhD registration fees at UK/EU student rate, research expenses and general training funds.

Candidates should direct initial expressions of interest to Tomasz J Guzik ()

Closing date for applications: 8 May 2019

Start date: to be discussed.

Funding Notes

RCUK rates: View Website

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