Don't miss our weekly PhD newsletter | Sign up now Don't miss our weekly PhD newsletter | Sign up now

  Role of RyR2 posttranslational modification in arrhythmias


   Department of Physiology

This project is no longer listed on FindAPhD.com and may not be available.

Click here to search FindAPhD.com for PhD studentship opportunities
  Assoc Prof Peter Jones  Applications accepted all year round  Competition Funded PhD Project (Students Worldwide)

About the Project

Cardiac arrhythmias remain the leading cause of death in patients with heart disease. An important trigger for arrhythmias is the inappropriate opening of the cardiac ryanodine receptor (RyR2). However, the mechanism by which these openings occur is not well understood. Phosphorylation is typically thought to increase the inappropriate opening of RyR2. However, we have preliminary evidence of a novel phosphorylation event that suppresses RyR2 function and protects against arrhythmias. Using protein biochemistry, biophysics, advanced imaging in ventricular myocytes and ECG measurements in transgenic animals; this project proposes to determine how this phosphorylation event controls RyR2 function.

Biological Sciences (4) Medicine (26)

Funding Notes

Students accepted into the PhD programme will be required to apply for a University of Otago PhD scholarship.
Full details of eligibility criteria for a PhD at the University of Otago can be found here: https://www.otago.ac.nz/graduate-research/prospective-students/otago662232.html
Full information on scholarships, including international grade requirements, can be found here: https://www.otago.ac.nz/graduate-research/scholarships/phd/index.html
Details of the English language requirements can be found here: https://www.otago.ac.nz/international/future-students/entrance-requirements/english-language-requirements/
Search Suggestions
Search suggestions

Based on your current searches we recommend the following search filters.