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  Self-assembly of engineered biopolymers and proteins toward functional materials


   Centre for Cell Factories and Biopolymers, Griffith Institute for Drug Discovery

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  Prof Bernd Rehm  Applications accepted all year round  Competition Funded PhD Project (Students Worldwide)

About the Project

Biopolymers and proteins can be bioengineered to self-assemble into defined hierarchical architectures. Here protein engineering will be applied to design proteins, which link biopolymers such as alginate, biopolyester and spider silk to form complex hybrid materials. Stimuli sensitive peptide linkers will be inserted to generate responsive materials that for example can release drugs upon cellular uptake. This project will explore the design space of diverse biological building blocks assembled into innovative unique materials providing solution for major health and environmental challenges.

Funding Notes

About the Scholarship

The 2019 Griffith University Postgraduate Research Scholarship has an annual stipend of $27,596 (indexed) for a period of up to three years of full-time study. Please see the GUPRS Conditions of Award for more information: https://www.griffith.edu.au/research-study/scholarships/guprs

A successful International applicant will also be awarded a Griffith University International Postgraduate Research Scholarship to cover tuition fees for up to three years. Please see the GUIPRS Conditions of Award for more information: https://www.griffith.edu.au/research-study/scholarships/guiprs

References

1. Rehm, B. H. A., Bioengineering towards self-assembly of particulate vaccines. Current Opinion in Biotechnology 2017, 48, 42-53.

2. Wong, J. X.; Rehm, B. H. A., Design of Modular Polyhydroxyalkanoate Scaffolds for Protein Immobilization by Directed Ligation. Biomacromolecules 2018, 19 (10), 4098-4112.

3. Du, J.; Rehm, B. H. A., Purification of target proteins from intracellular inclusions mediated by intein cleavable polyhydroxyalkanoate synthase fusions. Microbial Cell Factories 2017, 16 (1), 184.