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  Simulations of interactions of ions with biomolecules in aqueous solutions


   Physical and Computational Chemistry

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  Prof P Jungwirth  No more applications being accepted  Competition Funded PhD Project (Students Worldwide)

About the Project

Hydration of ions and their interaction with biomolecules plays an important role in many natural and technological processes. The PhD. study will focus on investigating specific ion effect ininteractions with molecules in water. Already in 1888 a German professor from Prague, Franz Hofmeister ordered ions into the so called lyotropic (Hofmeister) series according to their ability to salt out proteins. Using molecular simulations we will attempt at understanding the physical basisof this ion ordering and predict the influence of specific ions on biophysical and biochemical processes.

How to apply
To apply for a PhD study at IOCB Prague, you must hold a Master’s degree (MSc) or the equivalent of the MSc in similar field (four or five year undergraduate degree). The application can be submitted before obtaining the Master’s degree, however, the applicant should obtain the degree within five months after the application deadline.

For more information visit our website “Call for PhD applications 2019”:
https://www.uochb.cz/web/structure/797.html

You can apply online via our application form http://www.uochb.cz/phdapplication/index.php/PhDrecruitment

Enquiries
All general enquiries should be directed to Katerina Solcova ([Email Address Removed]). Scientific enquiries can be addressed to the supervisor ([Email Address Removed]).

Funding Notes

Regular monthly income of students at IOCB Prague varies depending on the faculty scholarship and supervisor's financial options.

References

1. Okur H.I., Hladílková J., Rembert K.B., Cho Y., Heyda J., Dzubiella J., Cremer P.S., Jungwirth P.: Beyond the Hofmeister Series: Ion Specific Effects on Proteins and Their Biological Functions. Journal of Physical Chemistry B (Feature Article) 121 (2017) 1997.
2. Kohagen M., Lepšík M., Jungwirth P.: Calcium Binding to Calmodulin by Molecular Dynamics with Effective Polarization. Journal of Physical Chemistry Letters 5 (2014) 3464.
3. Cremer P.S., Jungwirth P.: Beyond Hofmeister. Nature Chemistry 6 (2014) 261.