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Simulations of translocation processes in cellular membranes

  • Full or part time
  • Application Deadline
    Thursday, February 21, 2019
  • Competition Funded PhD Project (Students Worldwide)
    Competition Funded PhD Project (Students Worldwide)

Project Description

The dissertation will focus on molecular simulations aiming to unravel at the molecular level key processes connected with translocation across cell membranes. Particular attention is paid to effects due to oxidative stress, ions, and specific membrane-associated peptides and proteins that are involved in numerous human diseases.

How to apply

To apply for a PhD study at IOCB Prague, you must hold a Master’s degree (MSc) or the equivalent of the MSc in similar field (four or five year undergraduate degree). The application can be submitted before obtaining the Master’s degree, however, the applicant should obtain the degree within five months after the application deadline.

For more information visit our website “Call for PhD applications 2019”:
https://www.uochb.cz/web/structure/797.html

You can apply online via our application form http://www.uochb.cz/phdapplication/index.php/PhDrecruitment

Enquiries

All general enquiries should be directed to Katerina Solcova (). Scientific enquiries can be addressed to the supervisor ().

Funding Notes

Regular monthly income of students at IOCB Prague varies depending on the faculty scholarship and supervisor's financial options.

References

1. Timr S., Pleskot R., Kadlec J., Kohagen M., Magarkar A., Jungwirth P.: Membrane Binding of Recoverin: From Mechanistic Understanding to Biological Functionality. ACS Central Science 3 (2017) 868.
2. Melcrová A., Pokorná S., Pullanchery S., Kohagen M., Jurkiewicz P., Hof M., Jungwirth P., Cremer P.S.: The Complex Nature of Calcium Cation Interactions with Phospholipid Bilayers. Scientific Reports 6 (2016) 38035.
3. Robison A.D., Sun S., Poyton M.F., Johnson G.A., Pellois J.-P., Jungwirth P., Vazdar M., Cremer P.S.: Polyarginine Interacts More Strongly and Cooperatively than Polylysine With Phospholipid Bilayers. Journal of Physical Chemistry B 120 (2016) 9287.
4. Allolio C., Baxova K., Vazdar M., Jungwirth P.: Guanidinium Pairing Facilitates Membrane Translocation. Journal of Physical Chemistry B 120 (2016) 143.

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