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Statistical methods to find genes affecting the progression of disease

  • Full or part time
  • Application Deadline
    Thursday, December 05, 2019
  • Competition Funded PhD Project (Students Worldwide)
    Competition Funded PhD Project (Students Worldwide)

Project Description

In this project you will develop and apply new statistical methods to identify genes that affect the growth rates of abdominal aortic aneurysms, and genes that affect survival with idiopathic pulmonary fibrosis. The findings will indicate new approaches to treatment and management of these diseases.

These studies of disease progression can be biased by unknown factors that affect both the risk of developing disease and the course of disease once established. Our group has recently developed new statistical approaches to correct this bias, using the results of genome-wide association studies. A substantial part of this project will be evaluating and developing improved methods building on our initial approaches. This will require programming of statistical analyses and computer simulations, and you should therefore have a demonstrated aptitude for statistical programming.

You will also analyse large datasets in Leicester and Nottingham. You should therefore have an aptitude for working with big data and for presenting results to cross-institutional collaborators clearly and succinctly.

You will join one of the largest genetic epidemiology groups in the UK, with excellent opportunities for networking and career development in a fast moving and high profile area.

Entry Requirements

UK Bachelor Degree with at least 2:1 in a relevant subject or overseas equivalent.

University of Leicester English language requirements apply.

This project is available for UK/EU/International students.

How to Apply

Application advice and application link

https://le.ac.uk/study/research-degrees/funded-opportunities/wellcome-trust-2020

Funding Notes

This project is funded by the Wellcome Trust Doctoral Training Programme.

Stipend for the PhD: Year 1 £19,919; Year 2 £21,542; Year 3 £23,298; Year 4 £23,997 (rates as of September 2019).

4 year PhD fee waiver at UK/EU rates.

International applicants need to ensure they can fund the difference between UK/EU and international fees for the duration of their studies.

We also will offer 2 fully funded places to international applicants from Lower-middle income countries per year. These will provide a full overseas fee waiver and stipend for 4 years.

Related Subjects

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