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Stochastic modelling of populations of interacting cells with complex underlying phenotypes

  • Full or part time
  • Application Deadline
    Applications accepted all year round
  • Competition Funded PhD Project (Students Worldwide)
    Competition Funded PhD Project (Students Worldwide)

Project Description

Individual based models describe the stochastic evolution of interacting individuals-cells with different phenotypes. Reaction networks on the other hand describe the stochastic interactions between different phenotypes-molecular species within a single cell. Current literature focuses either on the population level with individuals having simple phenotypes or to reaction networks of single cells ignoring the interactions between cells. This project will attempt a joint modelling of these two levels. We will be interested to see the advantages of this approach particularly in terms of analysing cellular decision making and its sensitivity to multidimensional changes of their external environment.
A strong interest in molecular and cellular biology is required but previous experience is not necessary. Background in stochastic processes and stochastic differential equations will be beneficial.

Funding Notes

Multiple sources of scholarship funding are potentially available, including university, research council (EPSRC) and research group (CREEM). Some are open to international students, some to EU and some UK only.

Applicants should have a good first degree in mathematics, statistics or another discipline with substantial numerical component. Applicants with degrees in other subjects (e.g., biology) should have the equivalent of A-level/Higher mathematics, and experience using statistical methods; such candidates should discuss their qualifications with the Postgraduate Officer. A masters-level degree is an advantage.

Further details of the application procedure, including contact details for the Postgraduate Officer, are available at View Website

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