About the Project
This project explores the design and fabrication of effective models of the epithelial apical plasma membrane that are amenable to study by neutron reflectometry (NR) and other surface analytical techniques. Epithelial cells form barriers between tissues with the role of protecting and enclosing organs found, for example, in the gut wall and the outer surface of the body. The development of models will allow the expansion of NR to nutrient and drug absorption and to furthering our understanding of how and why molecules can cross these barriers, and will be used here in the study of polyphenol interactions within the GIT. In time, this work could be extended to modelling other membrane structures found in human and animal cells, such as the lateral and basal membranes.
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