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Studying the Key Link between DNA Mutation and Cancer, based on the Novel Mutation Test called the PigA Assay

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  • Full or part time
    Prof Gareth Jenkins
  • Application Deadline
    Applications accepted all year round
  • Self-Funded PhD Students Only
    Self-Funded PhD Students Only

Project Description

"Studying the Key Link between DNA Mutation and Cancer, based on the Novel Mutation Test called the PigA Assay."

This is a non–funded PhD opportunity available at Swansea University Medical School, and based in the state of the art Institute of Life Science suite of buildings. The recent UK Research Excellence Framework (REF) ranked Swansea Medical School as 2nd in the UK in “allied health professions”, and the “environment” was graded as 100% world class.

This project provides the opportunity to join a large, internationally respected research group which investigates the role of DNA mutation in cancer. This project will involve both clinical and fundamental science aspects. The successful student will further develop the PigA assay as a cancer screen and determine the factors controlling blood cell mutation using healthy volunteers (including dietary factors, lifestyle factors etc). The student will then utilise the PigA assay to measure DNA mutation in circulating red and white blood cells of patients who either have, or do not have, cancer. The mutation levels will be correlated with clinical data about the patients and will also study the effects of therapy (chemo/radiotherapy) on circulating mutation levels.

For more information about the project supervisor, Professor Gareth Jenkins, please visit:

Applicants are strongly advised to contact Professor Jenkins before applying for this project ([email protected]).


Applicants for research degrees must hold an initial degree of a UK University or another University approved by Senate and would normally have achieved or be predicted to achieve a minimum classification of upper second (2:1) or equivalent.

All candidates whose first language is not English are expected to pass IELTS (International English Language Testing System) at grade 6.5.

We appreciate there can often be no substitute for experience and thus candidates with a lower grade are encouraged to apply, providing they can demonstrate ’an advantage’ to make up for the lower academic grade. Applications from non graduates are also welcome.

Both UK/EU and international students are welcome to apply.

Funding Notes

There is no funding attached to this project and only self-funded students should apply.

How good is research at Swansea University in Allied Health Professions, Dentistry, Nursing and Pharmacy?
Allied Health professions

FTE Category A staff submitted: 44.90

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities

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