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Subcellular Targeting of Radiosensitizers and Radionuclides to Enhance Radiotherapy

  • Full or part time
  • Application Deadline
    Wednesday, February 26, 2020
  • Funded PhD Project (Students Worldwide)
    Funded PhD Project (Students Worldwide)

Project Description

Department of Oncology, Old Road Campus Research Building, Roosevelt Drive, Oxford

MCR: From: £37,327 p.a.

A fellowship position is available for a period of 36 months, tenable at Oxford University Department of Oncology (CRUK/MRC Institute for Radiation Oncology), working on a project entitled: “Subcellular Targeting of Radiosensitisers and Radionuclides to Enhance Radiotherapy” as part of the THERADNET ITN. The central aim of this project is to develop subcellular organelle-targeting oligonucleotide-based agents aimed at causing organelle functional disruption and radiosensitisation. Direct delivery of radiation to subcellular sites using oligonucleotide-based radionuclide-labelled compounds will also be tested.

The fellow will be considered to be both a registered student of the University being enrolled for a comprehensive PhD/DPhil training programme in the area of radiation research and also an employee.

The fellow will contribute to work in the laboratory concerning external beam radiotherapy, radionuclide therapy and radiobiology; contribute to the preparation of manuscripts for peer-review and publication in scientific journals; assist with the day-to-day running of the laboratory and supervise new scientists and students.

To be eligible for this post candidates must also be accepted by the University of Oxford as a DPhil student and continue to be a registered student for the duration of the employment contract. Assistance will be provided to candidates regarding the graduate admissions process. All graduate awards are subject to the Examination Regulations currently in force: see

To be eligible for this position, at the time of the fellowship start date, you must not already be in possession of a PhD or have more than 4 years of full-time equivalent research experience as measured from the award date of your first degree (BSc or equivalent).

Under the terms of the EC funding, which aims to promote mobility within the research community, to be eligible for the post you must not have been resident in the UK for more than a total of 12 months in the past 3 years up to the fellowship start date.

Other eligibility criteria are to hold at least a 2:1 (or equivalent) BSc or equivalent degree in a relevant field and to have experience of appropriate laboratory techniques with a good knowledge of cancer biology and radiation biology literature and the ability to design robust well controlled experiments.

The EC funding for this position provides for a remuneration starting from £37,327 p.a. Actual salary will depend on employer deductions, personal circumstances and the exchange rate applicable to the fellowship. This amount includes an annual living allowance and a mobility allowance (to cover the expenses associated with working in a different country). Under the terms of the EC funding, which aims to promote mobility within the research community, to be eligible for the post you must not have been resident in the UK for more than a total of 12 months in the past 3 years. Persons who have obtained a doctorate or had more than 4 years’ full-time research experience are ineligible.

Please note the post-holder will need to be available to start on 1 April 2020.

Further particulars for the post can be found in the job description. This is a full-time post and is funded for 3 years.

All applicants must complete an application form, THERADNET application form, upload a CV and supporting statement.

The closing date for applications is 12.00 noon on 26 February 2020.

Funding Notes

For applicants eligible for home / EU fees all college and tuition fees will be covered by the Oxford Institute for Radiation Oncology. Non-EU applicants must cover the additional fee element that is applied to non-EU students when undertaking a DPhil. We advise non-EU applicants to calculate their fees here prior to submitting their application to ensure they are aware of the total amount they will be liable for and establish if they have the means to pay. For the academic year 2020/2021, non-EU applicants will be required to pay £26,405 per year in additional fees.

How good is research at University of Oxford in Clinical Medicine?

FTE Category A staff submitted: 238.51

Research output data provided by the Research Excellence Framework (REF)

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