Candidates should have a biology, biochemistry or biomedical degree.
Candidates with a 1st class degree or laboratory experience will be at an advantage.
Candidates with evidence of strong mathematics/computing ability will be at a significant advantage.
This project is offered through the Midlands Integrative Biosciences Training Partnership please see the following link for details of eligability:
Human BRCA1-BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection. Nat Struct Mol Biol. 2016 Jul;23(7):647-55. doi: 10.1038/nsmb.3236. Epub 2016 May 30.
The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress. Nature. 2009 Dec 17;462(7275):886-90. doi: 10.1038/nature08593.
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9 Nat Biotechnol. 2016 Feb;34(2):184-191. doi: 10.1038/nbt.3437. Epub 2016 Jan 18.