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Synthesis and application of N-fluoroalkylated compounds

  • Full or part time
    Dr P Beier
  • Application Deadline
    Sunday, February 23, 2020
  • Competition Funded PhD Project (Students Worldwide)
    Competition Funded PhD Project (Students Worldwide)

Project Description

The recently reported synthesis of perfluoroalkyl azides and triazoles1 opened the door to study the properties and reactivity of these compounds. In this project, the rich chemistry of (per)fluoroalkyl azides and triazoles1-10 will be investigated and new synthetic approaches to underdeveloped N-fluoroalkyl-containing compounds such as azides, azoles, azirines, ureas, carbamates, and amides will be studied. This class of compounds is expected to find utilization in drug discovery and in the development of new materials.

How to apply

To apply for a PhD study at IOCB Prague, you must hold a Master’s degree (MSc) or the equivalent of the MSc in similar field (four or five year undergraduate degree). The application can be submitted before obtaining the Master’s degree, however, the applicant should obtain the degree within five months after the application deadline.

For more information visit our website “Call for PhD applications 2020”:
https://www.uochb.cz/en/phd-program

If you decided to apply, please do so online via our application form:
https://www.uochb.cz/en/call-for-phd-applications

Funding Notes

Regular monthly income of students at IOCB Prague varies depending on the faculty scholarship and supervisor's financial options.

References

1. Z. E. Blastik, S. Voltrová, V. Matoušek, B. Jurásek, D. W. Manley, B. Klepetářová, P. Beier Angew. Chem. Int. Ed. 2017, 56, 346.
2. S. Voltrová, M. Muselli, J. Filgas, V. Matoušek, B. Klepetářová, P. Beier Org. Biomol. Chem. 2017, 15, 4962.
3. V. Motornov, A. Markos, P. Beier Chem. Commun. 2018, 54, 3258.
4. Z. Blastik, B. Klepetářová, P. Beier Chem. Select 2018, 3, 7045.
5. S. Voltrová, I. Putovný, V. Matoušek, B. Klepetářová, P. Beier Eur. J. Org. Chem. 2018, 5087.
6. V. Motornov, P. Beier J. Org. Chem. 2018, 83, 15195.
7. A. Markos, S. Voltrová, V. Motornov, D. Tichý, B. Klepetářová, P. Beier Chem. Eur. J. 2019, 25, 7640.
8. V. Motornov, V. Košťál, A. Markos, D. Täffner, P. Beier Org. Chem. Front. 2019, 6, 3776.
9. S. Voltrová, J. Filgas, P. Slavíček, P. Beier Org. Chem. Front. DOI: 10.1039/c9qo01295h.
10. O. Bakhanovich, P. Beier Chem. Eur. J. DOI: 10.1002/chem.201903627.

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