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Synthesis of Glycolipid Probes to Study New Antibiotic Targets

  • Full or part time
  • Application Deadline
    Friday, February 28, 2020
  • Funded PhD Project (European/UK Students Only)
    Funded PhD Project (European/UK Students Only)

Project Description

A fully funded PhD studentship is available to work on the development of chemical probes to study novel antibiotic targets.

Antibiotic resistance is one of the most significant challenges facing our generation and we are in desperate need of new antibiotic targets. Bacteria use glycolipids for several important functions, with many different enzymes processing these biomolecules. Therefore, such glycolipid-processing enzymes could make excellent antibiotic targets. In this project, synthetic organic chemistry will be used to prepare chemically-labelled versions of bacterial glycolipids that can be used to study the mechanism and/or assay potential inhibitors of novel antibiotic targets.

A student with excellent practical skills and knowledge in the field of synthetic organic chemistry is required for this project. Applicants should clearly highlight their expertise in organic synthesis and why they believe they are ideal for this position in their application.

You will join the Cochrane Lab, a dynamic bio-organic chemistry research group committed to developing novel antimicrobial compounds and targets. Situated in the School of Chemistry and Chemical Engineering, we have state-of-the-art facilities required for all aspects of our multidisciplinary research.

This studentship is fully funded for 3 years and covers PhD tuition fees, together with a tax-free stipend. The studentship will commence in October 2020.
Candidates should hold or expect to gain a minimum of an upper second-class honours degree in chemistry or related discipline.

For more information, please contact Dr Stephen Cochrane ().

Funding Notes

Due to restrictions on the funding, this studentship is only open to candidates from the UK, or those that have been UK resident for the past three years (EU nationals only).

Related Subjects

How good is research at Queen’s University Belfast in Chemistry?

FTE Category A staff submitted: 34.35

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities

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