This is a 4 year BBSRC CASE studentship under the Newcastle-Liverpool-Durham DTP. The successful applicant will receive research costs, tuition fees and stipend (£15,009 for 2019-20). The PhD will start in October 2020. Applicants should have, or be expecting to receive, a 2.1 Hons degree (or equivalent) in a relevant subject. EU candidates must have been resident in the UK for 3 years in order to receive full support. Please note, there are 2 stages to the application process.
Coordination of capsule assembly and cell wall biosynthesis in Staphylococcus aureus. Nat Commun., 2019, 10: 1404.
A specialized MreB-dependent cell wall biosynthetic complex mediates the formation of stalk-specific peptidoglycan in Caulobacter crescentus. PLoS Genet., 2019, 15: e1007897.
Plasticity of Escherichia coli cell wall metabolism promotes fitness and antibiotic resistance across environmental conditions. eLife, 2019, 8: e40754.
On the antibacterial activity of azacarboxylate ligands: lowered metal ion affinities for some bis-amide derivatives of EDTA do not necessarily mean reduced activity. Chem. Eur. J., 2018, 24: 7137-7148.
Copper inhibits peptidoglycan LD-transpeptidases suppressing -lactam resistance due to by-pass of penicillin-binding proteins. Proc. Nat. Acad. Sci. USA, 2018, 115: 10786-10791.
Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division. Nat. Comm., 2018, 9: 5090.
Induced conformational changes activate the peptidoglycan synthase PBP1B. Mol. Microbiol., 2018, 110: 335-356.
Exploring the links between peptoid antibacterial activity and toxicity. Med. Chem. Comm., 2017, 8: 886-896
The redundancy of peptidoglycan carboxypeptidases ensures robust cell shape maintenance in Escherichia coli. mBio, 2016, 7: e00819-16.
Glycosylated nanoparticles as efficient antimicrobial delivery agents. Biomacromolecules, 2016, 17: 2672-2679.