Type 1 diabetes (T1D) is a chronic autoimmune disease which currently effects around 8.4 million individuals worldwide, and is set to double by 2040. Cardiovascular disease is the main cause of morbidity and mortality in individuals with T1D. Physical activity (PA) is widely promoted for individuals with T1D to reduce cardiovascular complications and improve health, however <20% of T1D individuals achieve physical activity guidelines with ‘fear of hypoglycaemia’ commonly cited as a the main barrier. Therefore, alternative methods for those unable or unwilling to engage in structured exercise are urgently needed.
Interrupting prolonged periods of sitting with short, frequent activity breaks is currently recommended in the guidelines World Health Organisation guideline. However, the evidence underpinning these recommendations remain preliminary and are focussed on those with or at risk of developing type 2 diabetes, as there is limited information regarding whether and how reducing sedentariness may be effective in those living with type 1 diabetes (T1D). Consequently, investigation of the effects of reduced sitting on glucose control and vascular function is of crucial importance. The findings of this work will inform the development of future interventions to improve health and wellbeing of individuals with T1D.
“The successful applicant will (a) conduct a systematic review exploring the associations between sedentary behaviour (SB), glucose regulation and vascular function in individuals with T1D, (b) assess the acute glucose and vascular responses to prolonged sitting (7hrs) versus breaking up prolonged sitting (2mins active break every 30mins), in sedentary individuals with T1D, and (c) investigate the effect of interrupting sitting with regular active breaks on glycaemia and daily insulin dose in sedentary individuals with T1D over a 1-month period, in a free-living environment.”
This project draws on the complimentary expertise of the supervisory team from the School of Sport, Exercise and Rehabilitation Sciences at University of Birmingham, and existing infrastructure (e.g., the newly established Movewell Centre in Gisbert Kapp). Techniques such as physical activity monitoring, continuous glucose monitoring, flow mediated dilation (FMD) and cerebral haemodynamics will be used. Multiple training and development opportunities will also be provided for the successful applicant.
How to apply
Applications should be directed to [Email Address Removed]. To apply, please send:
· Application form (see application link below)
· CV
· Academic transcripts
· Names and contact details of two referees
Nominated candidates will be interviewed on Thursday June 22 or Friday June 23.
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