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The expression of biomarkers, and correlation with clinical outcome measures, pre and post-surgical treatment of benign and malignant disorders of the penis.

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  • Full or part time
    Dr Stephen Hughes
    Mr I Shergill
  • Application Deadline
    Applications accepted all year round
  • Self-Funded PhD Students Only
    Self-Funded PhD Students Only

Project Description

Penile cancer is a rare cancer in Western countries. Around 550 men are diagnosed each year in the UK. 3 out of every 1,000 cancers diagnosed in men in the UK annually are penile cancer, although this number is increasing. It is more common in men who live in Asia, Africa or South America. The exact cause of penile cancer is not known but there are several risk factors such as infection with the human papilloma virus, smoking, age and a weakened immune system (Cancer Research UK).

The aim of our research study is to investigate changes in selective biomarkers after penile surgery for the treatment of benign disorders and cancer of the penis, and to test the hypothesis that changes to biomarkers are associated with cancer recurrence and progression, as well as post-operative complications.

For more information, please visit: http://www.biomedicalcpd.com/#!nw2urc/c1st6

*This work is in collaboration with Mr Manit Arya (University College London) but will be based at Chester, UK*

When applying for this study, please indicate to the University of Chester Graduate School - that this is for the attention of Dr Jon Power (Department of Biological Sciences).

Funding Notes

Self-funded PhD.

References

Arya M, Kalsi J, Kelly J, Muneer A. Malignant and premalignant lesions of the
penis. BMJ. 2013;346:f1149.

Ahmed HU, Arya M, Freeman A, Emberton M. Do low-grade and low-volume prostate cancers bear the hallmarks of malignancy? Lancet Oncol. 2012;13:e509-17

How good is research at University of Chester in Allied Health Professions, Dentistry, Nursing and Pharmacy?

FTE Category A staff submitted: 23.00

Research output data provided by the Research Excellence Framework (REF)

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