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The Influence of Compressibility on the Dynamics of Encapsulated Microbubbles

  • Full or part time
  • Application Deadline
    Friday, March 15, 2019
  • Competition Funded PhD Project (European/UK Students Only)
    Competition Funded PhD Project (European/UK Students Only)

Project Description

Thin-shell encapsulated microbubbles (EMBs) are gas-filled microbubbles encased in a stiff albumin or flexible lipid shell. They have been shown to improve the performance of biomedical procedures such as ultrasound contrast imaging, targeted drug delivery and sonoporation.

The viscoelastic fluid will be modelled using models such as the Oldroyd B model while the properties of the shell are accounted for through the dynamic boundary condition at the bubble surface.

An interdisciplinary approach combining models for cell mechanics with bubble dynamics will provide insights into the deformation of cellular entities subject to cavitation flow and to enhance drug delivery via coated microbubbles. Ultrasonic cavitation is one of the most effective cleaning agents. For example, it is used to clean and to disinfect surgical instruments in hospitals. There is a wide range of other biomedical applications that will benefit from the computational models developed in this project.

Funding Notes

UK Research Council eligibility conditions apply.

Full awards (fees plus maintenance stipend) are open to UK Nationals and EU students who can satisfy UK residency requirements. To be eligible for the full award, EU Nationals must have been in the UK for at least 3 years prior to the start of the course for which they are seeking funding, including for the purposes of full-time education.

References

Applicants should submit an application for postgraduate study via the Cardiff University Online Application Service.
http://www.cardiff.ac.uk/study/postgraduate/research/programmes/programme/mathematics

Applicants should select Doctor of Philosophy (Mathematics) with an entry date of October 2019

In the "Research proposal and Funding" section of your application, please specify the project title and supervisors of this project and copy the project description in the text box provided.

Please select “No, I am not self-funding my research” when asked whether you are self-funding your research.

Please add “EPSRC Doctoral Training Partnership PhD in Mathematics" when asked "Please provide the name of the funding you are applying for".

Related Subjects

How good is research at Cardiff University in Mathematical Sciences?

FTE Category A staff submitted: 24.05

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities

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