The post is open to EU/UK candidates and provides full tuition fees and a stipend at UKRI standard rates (currently £14,777 p.a.).
Some teaching duties may be required to be carried out during the PhD studentship.
1 "Near-field optical microscopy with an infra-red free electron laser applied to cancer diagnosis", Smith AD et al App. Phys. Lett. 102 053701 (2013)
2 "Imaging cervical cytology with scanning near-field optical microscopy (SNOM) coupled with an IR-FEL." Halliwell et. al. Scientific Reports, 6 29494 (2016)
3 “An evaluation of the application of the aperture infrared SNOM technique to biomedical imaging.” Ingham et. al. Biomed. Phys. Eng. Express 4 025011 (2018)
4 "Submicron infrared imaging of an oesophageal cancer cell with chemical specificity using an IR-FEL" Ingham, et. al. Biomed. Phys. Eng. Express 5 015009 (2018)
5 "SNOM Imaging of a Crypt-Like Feature in Adenocarcinoma Associated with Barrett’s Oesophagus" Craig T. et. al. Phys. Stat. Sol. B 1700518 (2018)
6 “Early detection of oral cancer using infrared imaging.” Cancer Research UK C7738/A26196
7 "Application of a quantum cascade laser aperture scanning near-field optical microscope to the study of a cancer cell" Smith CI et. al. Analyst 143 5912 (2018)
8 Fiorentzis M, et al. Conjunctival melanoma and electrochemotherapy: preliminary results using 2D and 3D cell culture models in vitro. Acta Ophthalmol. 2018 Dec 10. doi: 10.1111/aos.13993.
9 Leedale, J. et al. Modeling the dynamics of hypoxia inducible factor-1alpha (HIF-1alpha) within single cells and 3D cell culture systems. Math Biosci (2014) 258C, 33-43.
10 Sandt C et al. Use of infrared microspectroscopy to elucidate a specific chemical signature associated with hypoxia levels found in glioblastoma. Analyst (2016) 141, 870-883.
11 Al-Mutawa YK et al., Effects of hypoxic preconditioning on neuroblastoma tumour oxygenation and metabolic signature in a chick embryo model. Biosci Rep. 2018 Aug 29;38(4).
12 Kalirai H et al. Use of the chick embryo model in uveal melanoma. Ocular Oncology and Pathology, 2015 Apr;1(3):133-40
13 Herrmann A. et al., The chorioallantoic membrane of the chick embryo to assess tumor formation and metastasis. Methods Mol Biol. 2016;1464:97-105.
14 Swadi R et al., Optimising the chick chorioallantoic membrane xenograft model of neuroblastoma for drug delivery. BMC Cancer. 2018 Jan 4;18(1):28.