The Neurotrauma & Neuroprotection Laboratory uses a variety of in vivo and in vitro techniques to understand the pathophysiology of traumatic brain injury and to evaluate the efficacy of novel treatments for TBI such as noble gases. Recent work has shown that the noble gas xenon reduces secondary injury development and improves outcome and survival following blunt TBI in rodents.
Neurotrauma is a global healthcare issue. The detailed mechanisms by which TBI leads to the neuropathology are not fully understood. Nevertheless, there is increasing evidence that exposure to even a single TBI may lead to persistent debilitating symptoms, and increases the risk of developing chronic traumatic encephalopathy (CTE).
The aim of this project is to investigate the pathophysiology of TBI, and the resulting functional impairments, with a focus on locomotor and cognitive impairments. The work also aims to evaluate novel treatments for TBI that may limit or prevent the development of the TBI induced pathophysiology & impairments.
The project will involve in vivo models of traumatic brain injury, functional behavioural testing, and immunohistochemistry, combined with in vivo and in vitro electrophysiology.
Imperial College London provides excellent opportunities for research students' training. All students benefit from a full programme of training in research and transferable skills organised through the Graduate School.
The project is available for self funded students or those that are able to secure funding via competitive scholarships available within Imprial College London and outside.
How to apply:
Applicants should hold or expect to gain a first/upper second-class honours degree (or equivalent) and/or a Masters degree (merit or distinction) in a relevant subject, and have appropriate research experience gained in a university or industry environment. Please note that candidates must fulfil Imperial College admissions criteria. Applicants should send a CV, including publications if any, with contact details of three academic referees and a covering letter explaining their suitability for the position to Dr Robert Dickinson ([Email Address Removed]).
Closing date: December 2022
For more information please contact Dr Robert Dickinson ([Email Address Removed]). Information on the laboratory can be found at: http://www.imperial.ac.uk/people/r.dickinson
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