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The synthesis of new bile acids for drug discovery - industry-sponsored PhD Scholarship – Ferrier Research Institute, Victoria University of Wellington


   Ferrier Research Institute

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  Dr Andreas Luxenburger, Dr Lawrence Harris  Applications accepted all year round  Funded PhD Project (Students Worldwide)

About the Project

Ferrier’s steroid chemistry team is excited to announce the availability of an industry-sponsored PhD scholarship. This study is aimed at the synthesis of a new range of structurally modified bile acids for biological testing. Bile acids activate many signally pathways that can be targeted for the development of new therapeutics. Therefore, structural manipulation of bile acids represents an attractive approach to develop new bile acid-based drugs for the treatment of various liver and metabolic diseases as well as neurodegenerative diseases.

This work will be based at the Ferrier Research Institute, Victoria University of Wellington, at the Gracefield Research Centre, Wellington, New Zealand and will involve multi-step chemical syntheses of target compounds, their purification and characterisation by NMR and MS spectroscopy, HPLC analysis, etc. The PhD candidate must be in New Zealand or able to get to New Zealand to carry out this study. Drs Andreas Luxenburger and Lawrence Harris will be the supervisors.

Applicants who hold a BSc (Hons) or MSc in organic or medicinal chemistry, synthetic drug discovery or a related discipline with significant practical organic chemistry experience and are enthusiastic and passionate about research are encouraged to apply.


Funding Notes

Applicants are invited to apply for a fully funded three-year PhD scholarship and be eligible for admission to the PhD programme at Victoria University of Wellington. A GPA of 7.5 or greater (on a 9 point scale), 1st class honours or Master’s grade and demonstration of proficiency in English are essential. This position will carry an annual stipend of NZ$35,000 per annum for 3.5 years. International candidates receive the same package provided they reside in New Zealand for the duration of the project/study under student visa. The recipient needs to sign a University Research Scholarship contract and confidentiality agreement.

References

Please apply to our Postgraduate Coordinator Dr. Alison Daines via ferrierPGC@vuw.ac.nz to express your interest in this project and how this relates to your previous experience. When applying please ensure all required documents are attached:
* Detailed CV
* Degree certificates and academic transcripts (BSc (Hons) or MSc in organic or medicinal chemistry, synthetic drug discovery or a related discipline with significant
practical organic chemistry experience)
* Details of at least two referees
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