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Time-resolved spectroscopy for improved therapies and clinical interventions

Project Description

A PhD studentship is available in the group of Professor Colin Campbell (School of Chemistry, The University of Edinburgh; . The project is an interdisciplinary collaboration with Professor Robert Henderson and Dr Neil Finlayson (School of Engineering) and Dr Brian Smith (Renishaw plc).

Reference Number PHD19CJC1

Project Summary
Raman spectroscopy is a hugely informative technique for studying biological systems but its use is challenging because bulk background fluorescence often swamps the signal. We have developed a new type of detector employing Single Photon Avalanche Diodes that can be used to separate Raman photons from fluorescence photons on the basis of their arrival time. The successful applicant will investigate the use of this detector (incorporated into an imaging system) to separate Raman and Fluorescence for the assessment of liver health prior to transplant (where fluorescence dominates Raman signals associated with metabolic changes that may lead to transplant rejection), and for organ-on-chip devices where Raman gives complementary information to fluorescence e.g. correlating redox potential and pH with protein expression and activity.

In the first instance, informal enquiries (accompanied by a CV) should be directed to:
Professor Colin Campbell, School of Chemistry, University of Edinburgh, David Brewster Road, Edinburgh EH9 3FJ, UK.

The position will remain open until January 31st, 2020.

Equality and Diversity
The School of Chemistry holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. The University is a member of the Race Equality Charter and is a Stonewall Scotland Diversity Champion, actively promoting LGBT equality. The University has a range of initiatives to support a family friendly working environment. See our University Initiatives website for further information. University Initiatives website:

Funding Notes

The studentship is fully funded for 48 months and covers tuition fees and an annual stipend (starting at £15,009 per annum) for a candidate satisfying EPSRC criteria:
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How good is research at University of Edinburgh in Chemistry?
(joint submission with University of St Andrews)

FTE Category A staff submitted: 43.30

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities

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