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Tissue resident memory T cells in IBD: Determinants of disease distribution, recurrence and response to therapy?


Project Description

This PhD studentship offers an exciting opportunity to join an active research group interested in human mucosal immunology based in the Centre for Immunobiology at the Blizard Institute. Applications are invited from enthusiastic and ambitious graduates who have or expect to be awarded a good Honours degree (2i or equivalent) degree in Biomedical Science, Biology, Biochemistry or similar. Preference will given to candidates with strong knowledge of immunology and practical laboratory experience. The project is part of an ongoing collaboration between basic scientist and clinicians and will suit any individuals with a keen interest in translational immunology.

The aim of this project is to understand the contribution of tissue resident memory T cells to intestinal inflammation in patients with inflammatory bowel disease (IBD) and test the hypothesis that the relative contribution of resident and circulating memory cells to the disease burden in individual patients drives different patterns of disease and response to therapies that interrupt T cell trafficking.

The successful candidate will be based in our laboratories in the Blizard Institute in Whitechapel, the largest institute of Barts and The London School of Medical and Dentistry. Here, the successful candidate will have access to state-of-the-art core facilities (Flow Cytometry, Genome Centre) for use in this project and participate in a vibrant and supportive research environment.

Application enquiries can be sent to Dr Andrew Stagg at or Prof James Lindsay at . To apply, click on the ’Visit Website’ button below, and scroll down the page to find the links to apply online.

Funding Notes

The studentship is fully funded for 36 months (3 years) by Bowel & Cancer Research and will commence September 2019. It includes university fees and the student will receive a minimum tax free stipend per annum of £16,777. This studentship is open to UK citizens or those who have been resident in the UK for a period of 3 years or more.

How good is research at Queen Mary University of London in Clinical Medicine?

FTE Category A staff submitted: 144.11

Research output data provided by the Research Excellence Framework (REF)

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