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Towards clinical application of exhaled volatile organic compound biomarkers: optimising breath sampling methods.

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  • Full or part time
    Dr S Fowler
    Dr A Horsley
    Dr Maxim Wilkinson
  • Application Deadline
    Applications accepted all year round
  • Self-Funded PhD Students Only
    Self-Funded PhD Students Only

Project Description

Funding Notes

Applications are invited from self-funded students. This project has a Band 3 fee. Details of our different fee bands can be found on our website ( For information on how to apply for this project, please visit the Faculty of Biology, Medicine and Health Doctoral Academy website (

As an equal opportunities institution we welcome applicants from all sections of the community regardless of gender, ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.


Gangwisch, J. E. (2013). Seasonal variation in metabolism: Evidence for the role of circannual rhythms in metabolism. Hypertension Research, 36, 392–393.

Phillips, C., Parthaláin, N. Mac, Syed, Y., Deganello, D., Claypole, T., & Lewis, K. (2014). Short-term intra-subject variation in exhaled volatile organic compounds (VOCs) in COPD patients and healthy controls and its effect on disease classification. Metabolites, 4, 300–318.

Sukul, P., Oertel, P., Kamysek, S., & Trefz, P. (2017). Oral or nasal breathing? Real-time effects of switching sampling route onto exhaled VOC concentrations. Journal of Breath Research, 11, 027101.

Sukul, P., Trefz, P., Schubert, J. K., & Miekisch, W. (2014). Immediate effects of breath holding maneuvers onto composition of exhaled breath. Journal of Breath Research, 8, 037102.

Wilkinson, M., Maidstone, R., Loudon, A., Blaikley, J., White, I. R., Singh, D., Ray, D., Goodacre, R., Fowler, S. J., & Durrington, H. J. (2019). Circadian rhythm of exhaled biomarkers in health and asthma. European Respiratory Journal, 15, 1901068.

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