DNA repair is fundamental to life. Failing to launch DNA repair in the right place at the right time leads to a wide range of devastating human diseases, including cancers and developmental disorders. Research in DNA repair mechanisms thus advances our understanding of the genetic bases of genome instability-associated human syndromes. As such, not only does DNA repair research aid in disease risk assessment, it also provides invaluable insight in rational drug design and discovery. Insight in the regulation of DNA repair also contributes to the operational framework of emerging methodologies in gene-editing and gene replacement therapies.
About Michael Huen Laboratory
My research team at The University of Hong Kong is dedicated to understanding the molecular bases of DNA damage detection and repair processes. We work collaboratively using multi-disciplinary approaches to identify key players and events that drive genome integrity protection. For more information please visit: